Evidence map›Paper›PMID 41155694›Full record

ArticlePharmaceuticals (Basel, Switzerland)2025

Disproportionality Analysis of Oral Toxicities Associated with PI3K/AKT/mTOR Pathway Inhibitors Using the FAERS Database.

Monica Marni, Djamilla Simoens, Nicholas Romero, Walter Keith Jones, Simon Kaja

Abstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Monica MarniProgram in Pharmacovigilance, Stritch School of Medicine, Loyola University Chicago, 2160 S. First Ave., Maywood, IL 60153, USA.
Djamilla SimoensProgram in Pharmacovigilance, Stritch School of Medicine, Loyola University Chicago, 2160 S. First Ave., Maywood, IL 60153, USA.ORCID 0009-0001-4060-0268
Nicholas RomeroProgram in Pharmacovigilance, Stritch School of Medicine, Loyola University Chicago, 2160 S. First Ave., Maywood, IL 60153, USA.
Walter Keith JonesProgram in Pharmacovigilance, Stritch School of Medicine, Loyola University Chicago, 2160 S. First Ave., Maywood, IL 60153, USA.
Simon KajaProgram in Pharmacovigilance, Stritch School of Medicine, Loyola University Chicago, 2160 S. First Ave., Maywood, IL 60153, USA.ORCID 0000-0001-6878-521X

Funding

Immunotherapy for Ocular Surface DiseasesR24EY032440 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI JAIN, SANDEEP · 2021 to 2025
$8.3M
Dr. John P. and Therese E. Mulcahy Endowed Professorship in Ophthalmology N/AIllinois Society for the Prevention of Blindness N/ALoyola University Chicago Program in Pharmacovigilance N/ANEI NIH HHS R24 EY032440NIH HHS 1R24EY032440-05Richard A. Perritt M.D. Charitable Foundation N/A
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

alpelisibbreast cancercapivasertibCDK4/6everolimusFAERSHER2−HR+inavolisibpalbociclibpharmacovigilancePI3K/AKT/mTORstomatitis

Identifiers

PMID41155694
PMCPMC12567227

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.