Evidence map›Paper›PMID 41155681›Full record

ArticlePharmaceuticals (Basel, Switzerland)2025

Design of Hybrid Quinoline-Chalcone Compounds Against

Marcos Lorca, Gisela C Muscia, Jaime Mella, Luciana Thomaz, Jenicer K Yokoyama-Yasunaka, Daniel Moraga, Yeray A Rodriguez-Nuñez, Silvia E Asís, Mauro Cortez, Marco Mellado

Abstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Marcos LorcaFacultad de Ciencias de la Vida, Carrera de Química y Farmacia, Universidad Viña del Mar, Viña del Mar 2572002, Chile.ORCID 0000-0003-3729-0980
Gisela C MusciaDepartamento de Ciencias Químicas, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Junín 956, Ciudad Autónoma de Buenos Aires, Buenos Aires 1113, Argentina.ORCID 0000-0003-2501-7119
Jaime MellaInstituto de Química, Facultad de Ciencias, Universidad de Valparaíso, Av. Gran Bretaña 1111, Valparaíso 2360102, Chile.ORCID 0000-0002-2434-8461
Luciana ThomazInstitute of Biomedical Sciences, Department of Parasitology, University of São Paulo, Av. Prof. Lineu Prestes 1374, São Paulo 05508-220, Brazil.ORCID 0009-0004-8944-9679
Jenicer K Yokoyama-YasunakaInstitute of Biomedical Sciences, Department of Parasitology, University of São Paulo, Av. Prof. Lineu Prestes 1374, São Paulo 05508-220, Brazil.ORCID 0000-0002-8472-7500
Daniel MoragaLaboratorio de Fisiología, Departamento de Ciencias Biomédicas, Facultad de Medicina, Universidad de Tarapacá, Arica 1000000, Chile.ORCID 0000-0002-7128-8174
Yeray A Rodriguez-NuñezLaboratorio de Síntesis y Reactividad de Compuestos Orgánicos, Departamento de Ciencias Quimicas, Facultad de Ciencias Exactas, Universidad Andrés Bello, Santiago 8370146, Chile.ORCID 0000-0003-4935-876X
Silvia E AsísDepartamento de Ciencias Químicas, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Junín 956, Ciudad Autónoma de Buenos Aires, Buenos Aires 1113, Argentina.ORCID 0000-0002-3978-8638
Mauro CortezInstitute of Biomedical Sciences, Department of Parasitology, University of São Paulo, Av. Prof. Lineu Prestes 1374, São Paulo 05508-220, Brazil.ORCID 0000-0001-6536-4647
Marco MelladoCentro de Investigación en Ingeniería de Materiales, Universidad Central de Chile, Santiago 8330507, Chile.ORCID 0000-0001-9577-5180

Funding

Agencia Nacional de Investigación y Desarrollo SA77210078Brazilian Funding Agencies from the São Paulo State Research Support Foundation FAPESP Grants #2012/24105-3; #2020/13562-0; #2024/05757-7Coordination for the Improvement of Higher Education Personnel CAPES Finance Code #001National Council for Scientific and Technological Development CNPq Grant #443816/2014-0
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

2D-QSAR model3D-QSAR modelcomparative molecular similarity index Analysis-CoMSIAdrug designexperimental validationleishmaniasisquinoline–chalcone synthesis

Identifiers

PMID41155681
PMCPMC12566680

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.