Evidence map›Paper›PMID 41155647›Full record

ArticlePharmaceuticals (Basel, Switzerland)2025

New-Onset Diabetes After Transplantation in Renal Recipients: A Pilot Comparative Study of Immediate vs. Extended-Release Tacrolimus Formulation.

Ioana Adela Ratiu, Florin Bănică, Corina Moisa, Bianca Pașca, Daniela Gîtea, Iulia Dana Grosu, Gabriel Cristian Bako, Oliviu Voștinaru, Wael Abu Dayyih, Lorena Filip

Abstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ioana Adela RatiuFaculty of Medicine and Pharmacy, University of Oradea, 1st December Square 10, 410073 Oradea, Romania.ORCID 0000-0003-0879-1903
Florin BănicăFaculty of Medicine and Pharmacy, University of Oradea, 1st December Square 10, 410073 Oradea, Romania.
Corina MoisaFaculty of Medicine and Pharmacy, University of Oradea, 1st December Square 10, 410073 Oradea, Romania.
Bianca PașcaFaculty of Medicine and Pharmacy, University of Oradea, 1st December Square 10, 410073 Oradea, Romania.ORCID 0000-0002-1788-6042
Daniela GîteaFaculty of Medicine and Pharmacy, University of Oradea, 1st December Square 10, 410073 Oradea, Romania.
Iulia Dana GrosuDepartment of Internal Medicine II-Nephrology University Clinic, "Victor Babeș" University of Medicine and Pharmacy, Eftimie Murgu Sq. No.2, 300041 Timișoara, Romania.ORCID 0000-0003-2582-8560
Gabriel Cristian BakoFaculty of Medicine and Pharmacy, University of Oradea, 1st December Square 10, 410073 Oradea, Romania.
Oliviu VoștinaruFaculty of Pharmacy, University of Medicine and Pharmacy "Iuliu Hatieganu" Cluj-Napoca, Victor Babeș Street 8, 400012 Cluj-Napoca, Romania.
Wael Abu DayyihFaculty of Pharmacy, Mutah University, Al-Karak 61710, Jordan.ORCID 0000-0002-5832-7247
Lorena FilipFaculty of Pharmacy, University of Medicine and Pharmacy "Iuliu Hatieganu" Cluj-Napoca, Victor Babeș Street 8, 400012 Cluj-Napoca, Romania.ORCID 0000-0001-9469-3546

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tacrolimus is frequently used in immunosuppressive therapy in renal transplant patients and is characterized by high toxicity, a low therapeutic index, and great individual variability. For these reasons, correct dosing is important to ensure patient safety by reducing the incidence of adverse effects while maintaining an optimal blood level that prevents graft loss. New-onset diabetes after transplantation (NODAT) affects 15-30% of patients treated with tacrolimus, with potential differences between immediate-release (IR) and extended-release (ER) formulations.

Indexed as

drug dissolutionextended releaseimmediate releasenew-onset diabetes after transplantationrenal transplantationtacrolimus

Identifiers

PMID41155647
PMCPMC12566853

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.