Evidence map›Paper›PMID 41155643›Full record

ReviewPharmaceuticals (Basel, Switzerland)2025

Potential and Mechanism of Nobiletin in Diabetes Mellitus and Associated Complications.

Chuyun Zhao, Wenjie Lai, Yu Li, Kinfong Hong, Youhua Xu

Abstract readReview
In one paragraph

Review in Pharmaceuticals (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chuyun ZhaoSchool of Pharmacy, Faculty of Medicine & State Key Laboratory of Mechanism and Quality of Chinese Medicine, Macau University of Science and Technology, Macau 999078, China.ORCID 0009-0009-6908-2757
Wenjie LaiSchool of Pharmacy, Faculty of Medicine & State Key Laboratory of Mechanism and Quality of Chinese Medicine, Macau University of Science and Technology, Macau 999078, China.ORCID 0009-0001-5316-4696
Yu LiFaculty of Chinese Medicine, State Key Laboratory of Mechanism and Quality of Chinese Medicine, Medical Sciences Division, Macau University of Science and Technology, Taipa, Macau 999078, China.ORCID 0009-0007-6822-3963
Kinfong HongFaculty of Chinese Medicine, State Key Laboratory of Mechanism and Quality of Chinese Medicine, Medical Sciences Division, Macau University of Science and Technology, Taipa, Macau 999078, China.ORCID 0000-0001-8674-9343
Youhua XuSchool of Pharmacy, Faculty of Medicine & State Key Laboratory of Mechanism and Quality of Chinese Medicine, Macau University of Science and Technology, Macau 999078, China.

Funding

Science and Technology Development Fund of Macau No. 0022/2024/RIB1 and 0104/2024/AGJ
6 · The paper itself

Abstract

The incidence and mortality of diabetes have increased dramatically in recent decades. New strategies to treat diabetes and its complications with minimal side effects are urgently needed. New monomeric molecules extracted from herbs are an alternative medicine that is being explored as candidate drugs for the treatment of diabetes and its complications. Nobiletin, a citrus flavonoid, has recently received increasing attention in scientific research due to its properties in combating diabetes and its complications, while existing research is scattered and unsystematic. This article summarizes recent studies and reviews the potential therapeutic role of nobiletin in preventing and alleviating diabetes and its complications, aiming to provide promising strategies for the clinical management of diabetes and its complications.

Indexed as

diabetes mellitusdiabetic complicationsnobiletintangerine peel

Identifiers

PMID41155643
PMCPMC12567476

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.