Evidence map›Paper›PMID 41155623›Full record

ArticlePharmaceuticals (Basel, Switzerland)2025

The Association Between Serum Drug Concentration and a Flare in Rheumatoid Arthritis Patients Tapering TNF Inhibitors.

Zohra Layegh, Femke Hooijberg, Laura Boekel, Agnes E M Looijen, Elise van Mulligen, Floris C Loeff, Lisanne Dijk, Radboud J E M Dolhain, Theo Rispens, Gertjan J Wolbink and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Zohra LayeghAmsterdam Rheumatology and Immunology Center, Location Reade, Department of Rheumatology, Dr. Jan van Breemenstraat 2, 1056 AB Amsterdam, The Netherlands.
Femke HooijbergAmsterdam Rheumatology and Immunology Center, Location Reade, Department of Rheumatology, Dr. Jan van Breemenstraat 2, 1056 AB Amsterdam, The Netherlands.
Laura BoekelAmsterdam Rheumatology and Immunology Center, Location Reade, Department of Rheumatology, Dr. Jan van Breemenstraat 2, 1056 AB Amsterdam, The Netherlands.
Agnes E M LooijenDepartment of Rheumatology, Erasmus MC, Dr. Molewaterplein 40, 3015 GD Rotterdam, The Netherlands.ORCID 0000-0002-5280-2182
Elise van MulligenDepartment of Rheumatology, Erasmus MC, Dr. Molewaterplein 40, 3015 GD Rotterdam, The Netherlands.
Floris C LoeffSanquin Diagnostic Service, 1066 CX Amsterdam, The Netherlands.
Lisanne DijkSanquin Diagnostic Service, 1066 CX Amsterdam, The Netherlands.
Radboud J E M DolhainDepartment of Rheumatology, Erasmus MC, Dr. Molewaterplein 40, 3015 GD Rotterdam, The Netherlands.
Theo RispensSanquin Diagnostic Service, 1066 CX Amsterdam, The Netherlands.
Gertjan J WolbinkAmsterdam Rheumatology and Immunology Center, Location Reade, Department of Rheumatology, Dr. Jan van Breemenstraat 2, 1056 AB Amsterdam, The Netherlands.
Pascal H P de JongDepartment of Rheumatology, Erasmus MC, Dr. Molewaterplein 40, 3015 GD Rotterdam, The Netherlands.ORCID 0000-0001-6628-6222

Funding

ZonMw grant number 171102014
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

anti-drug antibodiesserum drug levelstapering TNF inhibitors

Identifiers

PMID41155623
PMCPMC12566885

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.