Evidence map›Paper›PMID 41155618›Full record

ArticlePharmaceuticals (Basel, Switzerland)2025

Intermedin Inhibits DNA Damage-Promoted Senescent Phenotype Transition of Vascular Smooth Muscle Cells in Aorta by Activating NAMPT/PARP1 in Mice.

Deng-Ren Ji, Yao Chen, Han-Xu Zhu, Shi-Meng Liu, Ning Wu, Ya-Rong Zhang, Jie Zhao, Yan-Rong Yu, Mo-Zhi Jia, Ling Han and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Deng-Ren JiLaboratory of Cardiovascular Bioactive Molecule, School of Basic Medical Sciences, Peking University, Beijing 100083, China.
Yao ChenDepartment of Physiology, School of Basic Medical Sciences, Chongqing Medical University, Chongqing 400016, China.
Han-Xu ZhuDepartment of Physiology, Nanjing Medical University, Nanjing 211166, China.
Shi-Meng LiuLaboratory of Cardiovascular Bioactive Molecule, School of Basic Medical Sciences, Peking University, Beijing 100083, China.ORCID 0000-0003-1523-8452
Ning WuDepartment of Obstetrics and Gynecology, Peking University First Hospital, Beijing 100034, China.
Ya-Rong ZhangLaboratory of Cardiovascular Bioactive Molecule, School of Basic Medical Sciences, Peking University, Beijing 100083, China.
Jie ZhaoLaboratory of Cardiovascular Bioactive Molecule, School of Basic Medical Sciences, Peking University, Beijing 100083, China.
Yan-Rong YuDepartment of Pathogen Biology, School of Basic Medical Sciences, Peking University, Beijing 100083, China.
Mo-Zhi JiaDepartment of Pathogen Biology, School of Basic Medical Sciences, Peking University, Beijing 100083, China.
Ling HanDepartment of Cardiology, Fu Xing Hospital, Capital Medical University, Beijing 100038, China.
Chao-Shu TangKey Laboratory of Molecular Cardiovascular Science, Ministry of Education, Peking University Health Science Center, Beijing 100083, China.
Lei-Lei ChenDepartment of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
Ye-Bo ZhouDepartment of Physiology, Nanjing Medical University, Nanjing 211166, China.
Yong-Fen QiLaboratory of Cardiovascular Bioactive Molecule, School of Basic Medical Sciences, Peking University, Beijing 100083, China.

Funding

the Beijing Natural Science Foundation 7212059the National Natural Science Foundation of China 31872790, 32271153, 32071113, 81970356
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

DNA damageintermedinNADPARP1senescent phenotype transitionvascular smooth muscle cells

Identifiers

PMID41155618
PMCPMC12567184

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.