Evidence map›Paper›PMID 41155560›Full record

ArticlePharmaceuticals (Basel, Switzerland)2025

Small-Molecule Tyrosine Kinase Inhibitors Modulate Glucose Handling in C2C12 Cell Line In Vitro: A Mechanistic Study.

Takudzwa Mugiya, Samarah Zvandasara, Mmamosheledi Mothibe, Phikelelani Ngubane, Andile Khathi, Ntethelelo Sibiya

Abstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Takudzwa MugiyaPharmacology Division, Faculty of Pharmacy, Rhodes University, Makhanda 6139, South Africa.
Samarah ZvandasaraPharmacology Division, Faculty of Pharmacy, Rhodes University, Makhanda 6139, South Africa.ORCID 0009-0004-4907-7778
Mmamosheledi MothibePharmacology Division, Faculty of Pharmacy, Rhodes University, Makhanda 6139, South Africa.ORCID 0000-0002-8613-2543
Phikelelani NgubaneSchool of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban 4001, South Africa.
Andile KhathiSchool of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban 4001, South Africa.ORCID 0000-0002-2246-0038
Ntethelelo SibiyaPharmacology Division, Faculty of Pharmacy, Rhodes University, Makhanda 6139, South Africa.ORCID 0000-0001-5894-8935

Funding

National Research Foundation TTK220318196
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AKT phosphorylationdiabetes mellitusglucose uptakeGLUT4 translocationsmall molecule tyrosine kinase inhibitor

Identifiers

PMID41155560
PMCPMC12566657

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.