Induction of Extrinsic Apoptotic Pathway in Pancreatic Cancer Cells by

Rinat Bar-Shalom, Lana Abdelhak, Wafa Zennouhi, Farid Khallouki, Laila Benbacer, Fuad Fares

Abstract read

In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rinat Bar-ShalomDepartment of Human Biology, Faculty of Natural Sciences, University of Haifa, Mount Carmel, Haifa 3498838, Israel.ORCID 0000-0001-8115-2388

Lana AbdelhakDepartment of Human Biology, Faculty of Natural Sciences, University of Haifa, Mount Carmel, Haifa 3498838, Israel.

Wafa ZennouhiTeam of Ethnopharmacology and Pharmacognosy, Biology Department, Faculty of Sciences and Techniques, Moulay Ismail University of Meknes, 52000 Errachidia, Morocco.ORCID 0009-0005-3567-8908

Farid KhalloukiTeam of Ethnopharmacology and Pharmacognosy, Biology Department, Faculty of Sciences and Techniques, Moulay Ismail University of Meknes, 52000 Errachidia, Morocco.

Laila BenbacerBiology Unit and Molecular Research, Department of Life Sciences, National Center for Energy, Sciences, and Nuclear Techniques (CNESTEN), P.O. Box 1382, 10001 Rabat, Morocco.

Fuad FaresDepartment of Human Biology, Faculty of Natural Sciences, University of Haifa, Mount Carmel, Haifa 3498838, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pancreatic cancer is an extremely deadly disease with few effective treatment options and the lowest survival rate among all types of cancer. As a result, there is an urgent need for the development of new and more effective treatment strategies. Natural products have long been a vital source of drug discovery, offering unique bioactive compounds, and representing a promising source for new, effective, and less toxic treatments. In the present study, we aimed to investigate the effects of

Indexed as

Antineoplastic Agents, PhytogenicApoptosisPancreatic NeoplasmsPlant ExtractsPlant RootsCaspase 3Cell Line, TumorCell ProliferationHumansSignal TransductionAntineoplastic Agents, PhytogenicCaspase 3Plant Extractsapoptosis inductioncaspasescytotoxicitynatural productspancreatic cancer therapyphytochemicals

Identifiers

PMID41155516

DOI10.3390/ijms262010221

PMCPMC12565304

What OpenQuestion holds

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LicenceCC BY

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.