Evidence map›Paper›PMID 41155473›Full record

ArticleInternational journal of molecular sciences2025

HLA Class II Alleles and Suicidal Behavior: Evidence from a Case-Control Study.

Mihaela Elvira Cîmpianu, Mihaela Laura Vică Matei, Ștefana Bâlici, Gheorghe Zsolt Nicula, Elena Maria Domșa, Teodora Cîmpianu, Sergiu Ionica Rusu, Horia George Coman, Costel Vasile Siserman

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mihaela Elvira CîmpianuDepartment of Cellular and Molecular Biology, Iuliu Haṭieganu University of Medicine and Pharmacy, 400006 Cluj-Napoca, Romania.ORCID 0000-0002-1647-9381
Mihaela Laura Vică MateiDepartment of Cellular and Molecular Biology, Iuliu Haṭieganu University of Medicine and Pharmacy, 400006 Cluj-Napoca, Romania.ORCID 0000-0003-0811-0821
Ștefana BâliciDepartment of Cellular and Molecular Biology, Iuliu Haṭieganu University of Medicine and Pharmacy, 400006 Cluj-Napoca, Romania.
Gheorghe Zsolt NiculaDepartment of Cellular and Molecular Biology, Iuliu Haṭieganu University of Medicine and Pharmacy, 400006 Cluj-Napoca, Romania.
Elena Maria DomșaDepartment of Social Sciences, "1st December 1918" University of Alba Iulia, 510009 Alba Iulia, Romania.
Teodora CîmpianuFaculty of Medicine, Iuliu Haṭieganu University of Medicine and Pharmacy, 400006 Cluj-Napoca, Romania.
Sergiu Ionica RusuFaculty of Sociology and Social Work, Babeș-Bolyai University, 400084 Cluj-Napoca, Romania.
Horia George ComanDepartment of Medical Psychology, Iuliu Haṭieganu University of Medicine and Pharmacy, 400006 Cluj-Napoca, Romania.
Costel Vasile SisermanLegal Medicine Institute, 400006 Cluj-Napoca, Romania.ORCID 0000-0002-6124-8582

Funding

"1st December 1918" University of Alba Iulia, Alba Iulia, RomaniaIuliu Hațieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania PCD no. 883/12/2022
6 · The paper itself

Abstract

Suicidality is a complex multifactorial phenomenon strongly associated with major depression and other psychiatric disorders. Building on evidence implicating the Major Histocompatibility Complex (MHC) in modulating the immune and inflammatory processes characterizing psychiatric disorders, we hypothesized that specific

Indexed as

AllelesHLA-DQ beta-ChainsHLA-DRB1 ChainsSuicideAdultCase-Control StudiesFemaleGenetic Predisposition to DiseaseGenotypeHaplotypesHumansMaleMiddle AgedSuicide, AttemptedYoung AdultHLA-DQB1 antigenHLA-DQ beta-ChainsHLA-DRB1 ChainsgenotypehaplotypeHLApsychosocial determinantsSSP-PCRsuicide attemptssuicide behavior

Identifiers

PMID41155473
PMCPMC12563147

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.