Evidence map›Paper›PMID 41155458›Full record

ArticleInternational journal of molecular sciences2025

The Prevalence of Second Neoplasms in Patients with Non-Aldosterone Producing Adrenocortical Lesions.

Paraskevi Tripolitsioti, Ariadni Spyroglou, Odysseas Violetis, Panagiota Konstantakou, Eleni Chouliara, Grigoria Betsi, Konstantinos Iliakopoulos, Eleni Memi, Konstantinos Bramis, Denise Kolomodi and 4 more

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Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

14 authors.

Paraskevi TripolitsiotiIntensive Care Unit, 1st Department of Respiratory Medicine, National and Kapodistrian University of Athens, Sotiria Hospital, 11527 Athens, Greece.
Ariadni Spyroglou2nd Department of Surgery, Aretaieio Athens Hospital, Medical School, National and Kapodistrian University of Athens, 11528 Athens, Greece.ORCID 0000-0001-9525-2275
Odysseas Violetis2nd Department of Surgery, Aretaieio Athens Hospital, Medical School, National and Kapodistrian University of Athens, 11528 Athens, Greece.
Panagiota Konstantakou2nd Department of Surgery, Aretaieio Athens Hospital, Medical School, National and Kapodistrian University of Athens, 11528 Athens, Greece.
Eleni Chouliara2nd Department of Surgery, Aretaieio Athens Hospital, Medical School, National and Kapodistrian University of Athens, 11528 Athens, Greece.
Grigoria BetsiEndocrinology & Diabetes Clinic, University Hospital of Heraklion, University of Crete, School of Medicine, 71500 Crete, Greece.
Konstantinos Iliakopoulos2nd Department of Surgery, Aretaieio Athens Hospital, Medical School, National and Kapodistrian University of Athens, 11528 Athens, Greece.ORCID 0000-0002-2527-7087
Eleni Memi2nd Department of Surgery, Aretaieio Athens Hospital, Medical School, National and Kapodistrian University of Athens, 11528 Athens, Greece.ORCID 0000-0002-4119-3051
Konstantinos Bramis2nd Department of Surgery, Aretaieio Athens Hospital, Medical School, National and Kapodistrian University of Athens, 11528 Athens, Greece.ORCID 0000-0002-2744-3042
Denise KolomodiEuropean Neuroendocrine Tumor Society (ENETS) Center of Excellence, Ekpa-Laiko Center, 11527 Athens, Greece.
Paraskevi XekoukiEndocrinology & Diabetes Clinic, University Hospital of Heraklion, University of Crete, School of Medicine, 71500 Crete, Greece.
Manousos Konstadoulakis2nd Department of Surgery, Aretaieio Athens Hospital, Medical School, National and Kapodistrian University of Athens, 11528 Athens, Greece.
George Mastorakos2nd Department of Surgery, Aretaieio Athens Hospital, Medical School, National and Kapodistrian University of Athens, 11528 Athens, Greece.ORCID 0000-0002-1929-3275
Krystallenia I Alexandraki2nd Department of Surgery, Aretaieio Athens Hospital, Medical School, National and Kapodistrian University of Athens, 11528 Athens, Greece.ORCID 0000-0003-2398-6768

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Over the last few decades, due to improvement in imaging techniques, the increased detection of adrenal incidentalomas is observed. Non-aldosterone producing adrenal adenomas (NAPACAs) often co-exist with second benign or malignant lesions. In the present study, we aimed to assess the presence of second neoplasms, both benign and malignant, in patients with NAPACAs, and to investigate possible correlations with clinical parameters, hormonal characteristics and the emergence of comorbidities. A total of 130 NAPACA patients were included in this single-center retrospective study. In this cohort, 35.4% of NAPACA patients carried any second neoplasm (either benign or malignant) whereas, 26.9% had a second malignant neoplasm. Cortisol levels after 1 mg overnight dexamethasone suppression test (F-ODS) were significantly higher in patients without a second neoplasm (

Indexed as

Adrenal Cortex NeoplasmsAdrenal Gland NeoplasmsAdrenocortical AdenomaNeoplasms, Second PrimaryAdultAgedAldosteroneFemaleHumansHydrocortisoneMaleMiddle AgedPrevalenceRetrospective StudiesAldosteroneHydrocortisonenon-aldosterone producing adrenal adenomas (NAPACA)second malignancysecond neoplasm

Identifiers

PMID41155458
PMCPMC12562571

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.