ReviewInternational journal of molecular sciences2025
MicroRNAs in Tissue Regeneration: Lessons from Animal Models.
Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- MiRNA Atlas: A Literature-Derived Database of MicroRNAs Bridging Osteoarthritis and Appendage Regeneration.bioRxiv : the preprint server for biology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
MicroRNAs (miRNAs) are a class of small noncoding RNAs that regulate gene expression. Over the past two decades, multiple studies have established the importance of miRNAs in regulating a variety of biological processes, one of which includes regenerative repair. Although many miRNAs have been shown to regulate the expression of genes that are required for regeneration, few studies have extrapolated these findings from cell culture to in vivo animal models or reported comparative work between regenerating and non-regenerating systems. Here, we review the most current literature highlighting the role of distinct miRNAs in regulating the repair of different tissues, focusing on the heart, limb and spinal cord. In exploring existing work, we emphasize the importance of using animal models to provide foundational knowledge that could potentially lead to future therapeutic strategies to allow for functional regenerative repair in humans.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.