Evidence map›Paper›PMID 41155263›Full record

ArticleInternational journal of molecular sciences2025

Cytotoxicity of

Sithenkosi Mlala, Opeoluwa Oyehan Oyedeji, Gbemisola Morounke Saibu, Mavuto Gondwe, Adebola Omowunmi Oyedeji

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sithenkosi MlalaDepartment of Chemistry, Faculty of Science and Agriculture, University of Fort Hare, Private Bag X1314, Alice 5700, South Africa.ORCID 0000-0002-4872-5700
Opeoluwa Oyehan OyedejiDepartment of Chemistry, Faculty of Science and Agriculture, University of Fort Hare, Private Bag X1314, Alice 5700, South Africa.ORCID 0000-0002-1240-3718
Gbemisola Morounke SaibuDepartment of Chemical and Physical Sciences, Faculty of Natural Sciences, Walter Sisulu University, Private Bag X1, Mthatha 5117, South Africa.
Mavuto GondweDepartment of Human Biology, Faculty of Health Sciences, Walter Sisulu University, Private Bag X1, Mthatha 5117, South Africa.ORCID 0000-0002-1684-801X
Adebola Omowunmi OyedejiDepartment of Chemical and Physical Sciences, Faculty of Natural Sciences, Walter Sisulu University, Private Bag X1, Mthatha 5117, South Africa.ORCID 0000-0001-8765-7766

Funding

NRF and Sasol Inzalo Foundation Grant No: 145788
6 · The paper itself

Abstract

According to the World Health Organization, cancer is still the leading cause of death for humans worldwide. Although over 100 chemotherapeutic agents are currently available for the treatment of cancer patients, the overall long term clinical benefit is disappointing due to the lack of effectiveness or severe side effects from these drugs. The use of complementary and alternative medicinal products from plants has continued to increase in past decades, due to fewer side effects of bioactive compounds from medicinal plants of which pentacyclic triterpenoids have been identified as one class of secondary metabolites that could play an important role in the treatment and management of a number of non-communicable diseases. The main aim of this study is to extract, isolate, identify, and elucidate pentacyclic triterpenoid (ursolic acid, UA (

Indexed as

Antineoplastic Agents, PhytogenicOleanolic AcidPlant ExtractsTriterpenesCell Line, TumorCell SurvivalHumansUrsolic AcidAntineoplastic Agents, PhytogenicOleanolic AcidPlant ExtractsTriterpenesUrsolic Acid3-acetylursolic-methylate3-O-acetyl ursolic acidcancercytotoxicityHepG2KMST-6MDAPC3ursolic-28-methylateursolic acid

Identifiers

PMID41155263
PMCPMC12562781

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.