Evidence map›Paper›PMID 41155207›Full record

ArticleInternational journal of molecular sciences2025

Clinical Impact of LAG3 Single-Nucleotide Polymorphism in DLBCL Treated with CAR-T Cell Therapy.

Katja Seipel, Sophia Maria Spahr, Inna Shaforostova, Ulrike Bacher, Henning Nilius, Thomas Pabst

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Elevated Allele Frequency and Male-Predominance of a CommonCurrent issues in molecular biology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Katja SeipelDepartment of Medical Oncology, Inselspital, Bern University Hospital, 3010 Bern, Switzerland.ORCID 0000-0003-3128-1573
Sophia Maria SpahrDepartment of Medical Oncology, Inselspital, Bern University Hospital, 3010 Bern, Switzerland.ORCID 0009-0004-6919-7216
Inna ShaforostovaDepartment of Medical Oncology, Inselspital, Bern University Hospital, 3010 Bern, Switzerland.
Ulrike BacherDepartment of Hematology, Inselspital, Bern University Hospital, 3010 Bern, Switzerland.ORCID 0000-0001-8771-947X
Henning NiliusDepartment of Clinical Chemistry, Inselspital, Bern University Hospital, 3010 Bern, Switzerland.ORCID 0000-0002-1323-3116
Thomas PabstDepartment of Medical Oncology, Inselspital, Bern University Hospital, 3010 Bern, Switzerland.ORCID 0000-0002-6055-5257

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lymphocyte-activation gene 3 (

Indexed as

Antigens, CDImmunotherapy, AdoptiveLymphoma, Large B-Cell, DiffusePolymorphism, Single NucleotideAdultAgedFemaleHumansLymphocyte Activation Gene 3 ProteinMaleMiddle AgedReceptors, Chimeric AntigenTreatment OutcomeAntigens, CDLag3 protein, humanLymphocyte Activation Gene 3 ProteinReceptors, Chimeric AntigenAxicaptagene ciloleucel (Yescarta©)B-lymphocyte antigen CD19chimeric antigen receptor (CAR)cytotoxic T-lymphocyte-associated protein 4 (CTLA-4)Lisocabtagene Maraleucel (Breyanzi©)lymphocyte activation gene 3 (LAG3)minor allele frequency (MAF)single nucleotide polymorphism (SNP)Tisagenlecleucel (Kymriah©)

Identifiers

PMID41155207
PMCPMC12562627

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.