ArticleBioengineering (Basel, Switzerland)2025
Design and Performance Assessment of a High-Resolution Small-Animal PET System.
Article in Bioengineering (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Initial Performance of a Prototype Small Animal PET Scanner Consisting of Long Semi-Monolithic Scintillator Detectors.Sensors (Basel, Switzerland) · 2026Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
This work reports the performance evaluation of a newly developed small-animal positron emission tomography (PET) system based on lutetium-yttrium oxyorthosilicate (LYSO) crystals and multi-pixel photon counter (MPPC). Performance was evaluated, including spatial resolution, system sensitivity, energy resolution, scatter fraction (SF), noise-equivalent count rate (NECR), micro-Derenzo phantom imaging, and in vivo imaging of mice and rats. The system achieved a tangential spatial resolution of 0.9 mm in the axial direction at a quarter axial offset using the three-dimensional ordered-subsets expectation maximization (3D OSEM) reconstruction algorithm. The peak sensitivity was 8.74% within a 200-750 keV energy window, with an average energy resolution of 12.5%. Scatter fractions were 12.9% and 30.0% for mouse- and rat-like phantoms, respectively. The NECR reached 878.7 kcps at 57.6 MBq for the mouse phantom and 421.4 kcps at 63.2 MBq for the rat phantom. High-resolution phantom and in vivo images confirmed the system's capability for quantitative, high-sensitivity small-animal imaging, demonstrating its potential for preclinical molecular imaging studies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.