Evidence map›Paper›PMID 41154889›Full record

SynthesisInternational journal of environmental research and public health2025

The Relationship Between Climate Change and Breast Cancer and Its Management and Preventative Implications in South Africa.

Pululu Sexton Mahasa, Muambangu Jean Paul Milambo, Sibusiso Frank Nkosi, Geofrey Mukwada, Martin Munene Nyaga, Solomon Gebremariam Tesfamichael

Abstract readSystematic Review
In one paragraph

Synthesis in International journal of environmental research and public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Pululu Sexton MahasaDivision of Public Health, Faculty of Health Sciences, University of the Free State, Bloemfontein 9300, South Africa.ORCID 0000-0003-1502-9554
Muambangu Jean Paul MilamboDivision of Public Health, Faculty of Health Sciences, University of the Free State, Bloemfontein 9300, South Africa.ORCID 0000-0003-0552-5378
Sibusiso Frank NkosiDivision of Public Health, Faculty of Health Sciences, University of the Free State, Bloemfontein 9300, South Africa.
Geofrey MukwadaDepartment of Geography, University of the Free State, Qwaqwa Campus, Phuthaditjhaba 9866, South Africa.ORCID 0000-0003-3159-9717
Martin Munene NyagaNext Generation Sequencing Unit, Division of Virology, School of Biomedical Sciences, Faculty of Health Sciences, University of the Free State, Bloemfontein 9300, South Africa.ORCID 0000-0002-5017-5584
Solomon Gebremariam TesfamichaelDepartment of Geography, Environmental Management and Energy Studies, University of Johannesburg, Johannesburg 2006, South Africa.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review aims to explore the implications of climate change for breast cancer management and prevention, with a focus on global strategies and interventions that can be applied in various contexts, including South Africa. Climate change has emerged as a significant global health concern, with far-reaching implications for various diseases, including cancer. This systematic review aims to synthesise epidemiological research examining the relationship between climate change and the incidence of breast cancer. We conducted a comprehensive literature search using main search terms, including "breast cancer," "climate change," "air pollution," "water pollution," "global warming," and "greenhouse effect," supplemented by the general term "breast" cancer across multiple databases. Our analysis identified studies that link environmental changes-such as rising temperatures, altered precipitation patterns, and increased exposure to pollutants-with breast cancer risk. Our findings highlight a potential association between climate-related factors, including heat stress, air and water pollution, endocrine-disrupting chemicals, and lifestyle changes influenced by environmental shifts, and the epidemiology of breast cancer. This review underscores the need for an integrated approach that incorporates climate science into public health strategies to mitigate breast cancer risk. By elucidating these connections, we aim to inform policymakers and healthcare professionals about the importance of addressing climate change not just as an environmental issue, but as a pressing determinant of health that may exacerbate cancer incidence, particularly in vulnerable populations. Further research is warranted to elucidate the underlying biological mechanisms and to develop targeted interventions that can address both climate change and its potential health impacts.

Indexed as

Breast NeoplasmsClimate ChangeFemaleHumansIncidenceSouth Africa2,3,7,8-tetrachloridibenzo-p-dioxin (TCDD or Dioxin)2,4-dichlorophenoxyacetic acidair pollutionbreast cancerclimate changeendocrine-disrupting chemicals (EDCs)oral contraceptive pillspesticidesphthalatespolybrominated diphenyl ethers (PBDEs)polychlorinated biphenyls (PCBs)p,p’dichlorodiphenyldichloroethylene (DDE)p,p’-dichlorodiphenyltrichloroethane (DDT)resveratrol (RES)rising temperatureUV radiation

Identifiers

PMID41154889
PMCPMC12563603

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.