Evidence map›Paper›PMID 41154841›Full record

ReviewBiology2025

Human Blastoid: A Next-Generation Model for Reproductive Medicine?

Anfisa S Ryabchenko, Vepa K Abdyev, Ekaterina A Vorotelyak, Andrey V Vasiliev

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Anfisa S RyabchenkoKoltzov Institute of Developmental Biology of the Russian Academy of Sciences, Moscow 119334, Russia.ORCID 0000-0003-4998-1367
Vepa K AbdyevKoltzov Institute of Developmental Biology of the Russian Academy of Sciences, Moscow 119334, Russia.ORCID 0000-0001-5697-3774
Ekaterina A VorotelyakKoltzov Institute of Developmental Biology of the Russian Academy of Sciences, Moscow 119334, Russia.ORCID 0000-0001-5405-0212
Andrey V VasilievKoltzov Institute of Developmental Biology of the Russian Academy of Sciences, Moscow 119334, Russia.

Funding

The government basic research program at the Koltzov Institute of Developmental Biology of the Russian Academy of Sciences in 2025 0088-2024-0013
6 · The paper itself

Abstract

Human early embryogenesis remains unexplored due to limited access to human embryos for research purposes. Meanwhile, the number of natural early pregnancy terminations remains significant, and solving the problem requires a deep understanding of the developmental mechanisms of this period. Although assisted reproductive technologies (ART) utilize up-to-date approaches in culturing human embryos

Indexed as

ART (assisted reproductive technology)blastocyst-like structuresblastoidimplantation modelpluripotent stem cellsself-organizationsynthetic embryology

Identifiers

PMID41154841
PMCPMC12562090

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.