Evidence map›Paper›PMID 41154818›Full record

ArticleBiology2025

Elucidating the Molecular Basis of Thermal Stress Response in Juvenile Turbot (

Xiatian Chen, Tao Gao, Ziwen Wang, Shuaiyu Chen, Nan Zhang, Xiaoming Zhang, Yudong Jia

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xiatian ChenState Key Laboratory of Mariculture Biobreeding and Sustainable Goods, Yellow Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Qingdao 266071, China.
Tao GaoState Key Laboratory of Mariculture Biobreeding and Sustainable Goods, Yellow Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Qingdao 266071, China.
Ziwen WangState Key Laboratory of Mariculture Biobreeding and Sustainable Goods, Yellow Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Qingdao 266071, China.
Shuaiyu ChenState Key Laboratory of Mariculture Biobreeding and Sustainable Goods, Yellow Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Qingdao 266071, China.
Nan ZhangState Key Laboratory of Mariculture Biobreeding and Sustainable Goods, Yellow Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Qingdao 266071, China.
Xiaoming ZhangState Key Laboratory of Mariculture Biobreeding and Sustainable Goods, Yellow Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Qingdao 266071, China.
Yudong JiaState Key Laboratory of Mariculture Biobreeding and Sustainable Goods, Yellow Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Qingdao 266071, China.

Funding

Central Public-interest Scientific Institution Basal Research Fund 2023TD81Central Public-interest Scientific Institution Basal Research Fund 20603022025013Central Public-interest Scientific Institution Basal Research Fund BRESG-JB202518Qingdao Postdoctoral Science Foundation under Grant QDBSH20240102012
6 · The paper itself

Abstract

Temperature has always been an important environmental factor, and changes in water temperature are closely related to the entire life process of fish. Investigating the impact of thermal stress on fish physiology is critical for optimizing aquaculture. This study employed transcriptomic and metabolomic approaches to investigate temperature-induced variations in the gene expression and metabolic profiles of turbot. The results showed that thermal stress could induce abnormal genes transcription, and functional annotation demonstrated predominant associations of these genes with key pathways including PI3K-Akt signaling, PPAR regulation, steroid biosynthesis, fatty acid metabolism, and FoxO signaling cascade. Metabolomic analysis revealed that amino acid metabolism was dysregulated, such as valine, leucine, and isoleucine. Joint analysis revealed significant positive associations between

Indexed as

correlation analysisgene expressionmetabolitethermal stressturbot (Scophthalmus maximus)

Identifiers

PMID41154818
PMCPMC12561631

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.