Evidence map›Paper›PMID 41154711›Full record

ArticleBiomolecules2025

Arctic Diatoms as a Source of Antibiofilm Compounds: Identification of Methyl 3-Hydroxyoctadecanoate and Pheophorbide

Marit Huizer, Renate Osvik, Espen H Hansen, Terje Vasskog, Jeanette H Andersen, Kim van Wezel, Hans Christian Eilertsen, Johan Isaksson, Kine Ø Hansen, Richard A Ingebrigtsen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Marit HuizerNatural Products and Medicinal Chemistry Research Group, Department of Pharmacy, UiT-The Arctic University of Norway, NO-9037 Tromsø, Norway.ORCID 0000-0002-1946-0600
Renate OsvikMarbio, Norwegian College of Fishery Science, UiT-The Arctic University of Norway, NO-9037 Tromsø, Norway.
Espen H HansenMarbio, Norwegian College of Fishery Science, UiT-The Arctic University of Norway, NO-9037 Tromsø, Norway.ORCID 0000-0003-0354-986X
Terje VasskogNatural Products and Medicinal Chemistry Research Group, Department of Pharmacy, UiT-The Arctic University of Norway, NO-9037 Tromsø, Norway.
Jeanette H AndersenMarbio, Norwegian College of Fishery Science, UiT-The Arctic University of Norway, NO-9037 Tromsø, Norway.ORCID 0000-0002-6059-060X
Kim van WezelMarbio, Norwegian College of Fishery Science, UiT-The Arctic University of Norway, NO-9037 Tromsø, Norway.ORCID 0009-0001-0140-2066
Hans Christian EilertsenMicroalgae and Microbiomes, Norwegian College of Fishery Science, UiT-The Arctic University of Norway, NO-9037 Tromsø, Norway.
Johan IsakssonNatural Products and Medicinal Chemistry Research Group, Department of Pharmacy, UiT-The Arctic University of Norway, NO-9037 Tromsø, Norway.ORCID 0000-0001-6287-7594
Kine Ø HansenNatural Products and Medicinal Chemistry Research Group, Department of Pharmacy, UiT-The Arctic University of Norway, NO-9037 Tromsø, Norway.ORCID 0000-0002-9023-1958
Richard A IngebrigtsenMicroalgae and Microbiomes, Norwegian College of Fishery Science, UiT-The Arctic University of Norway, NO-9037 Tromsø, Norway.ORCID 0000-0002-2871-8888

Funding

The Research Council of Norway 328654
6 · The paper itself

Abstract

Marine diatoms are prolific producers of bioactive metabolites, but Arctic species remain underexplored as sources of antibacterial and antibiofilm agents. Here, seven species were grown in photobioreactors (PBRs) and systematically screened for antibacterial, antibiofilm, and cytotoxic activities. All strains inhibited Gram-positive bacteria, and four reduced

Indexed as

Anti-Bacterial AgentsBiofilmsChlorophyllDiatomsArctic RegionsMicrobial Sensitivity TestsStaphylococcus epidermidisAnti-Bacterial AgentsChlorophyllpheophorbide aantibacterial activityantibiofilm activityarctic marine diatomsbioprospectingmethyl 3-hydroxyoctadecanoatemicroalgaepheophorbide aphotobioreactor cultivationsecondary metabolites

Identifiers

PMID41154711
PMCPMC12562383

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.