ReviewBiomolecules2025
The Clinical Implications of Progesterone in Preeclampsia.
Review in Biomolecules, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
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Authors and funding
2 authors.
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Abstract
Preeclampsia is a severe complication affecting both maternal and neonatal health and is becoming a significant global public health issue. As a vital steroid hormone, progesterone (P4) plays a crucial role during pregnancy and in regulating various physiological processes. Recent studies have indicated that P4 is not only involved in pregnancy maintenance, but may also be closely related to preeclampsia pathogenesis and prevention. Previous research has suggested that P4 may participate in the mechanism of preeclampsia by regulating vascular function, immune responses, and placental function. Moreover, key enzymes and metabolites involved in the synthesis and metabolism of P4 are also associated with preeclampsia onset. Additionally, the potential value of clinically applying P4 in preventing and treating preeclampsia has been shown; however, the corresponding clinical practices require further validation and optimization. This study aimed to review the physiological effects, pathological functions, and clinical applications of P4 in preeclampsia, providing evidence for future research and clinical practice.
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Registered trials
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