Evidence map›Paper›PMID 41154664›Full record

ArticleBiomolecules2025

AlphaFold-Guided Semi-Rational Engineering of an (

Xiaole Yang, Xia Tian, Ruizhou Tang, Jiahuan Li, Xuning Zhang, Tingting Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Engineering of ω-transaminases for advanced applications.Applied microbiology and biotechnology · 2026
    Review
  2. SPIN-guided engineering of a novel (Synthetic and systems biotechnology · 2026
    Article
  3. The transformative power of structural predictions with AI in plant science.The Plant journal : for cell and molecular biology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xiaole YangJiangsu Key Laboratory of Marine Pharmaceutical Compound Screening, Jiangsu Ocean University, Lianyungang 222005, China.
Xia TianJiangsu Key Laboratory of Marine Pharmaceutical Compound Screening, Jiangsu Ocean University, Lianyungang 222005, China.
Ruizhou TangJiangsu Key Laboratory of Marine Pharmaceutical Compound Screening, Jiangsu Ocean University, Lianyungang 222005, China.
Jiahuan LiJiangsu Key Laboratory of Marine Pharmaceutical Compound Screening, Jiangsu Ocean University, Lianyungang 222005, China.
Xuning ZhangJiangsu BestEnzymes Biotech Co., Ltd., Lianyungang 222005, China.
Tingting LiJiangsu Key Laboratory of Marine Pharmaceutical Compound Screening, Jiangsu Ocean University, Lianyungang 222005, China.

Funding

Jiangsu Ocean University for start-up funds KQ19026Natural Science Foundation of The Jiangsu Higher Education Institutions of China 24KJB150007
6 · The paper itself

Abstract

Chiral amines are vital structural motifs in pharmaceuticals and agrochemicals, where enantiomeric purity governs bioactivity and environmental behavior. We identified a novel (

Indexed as

AminesMycobacteriumProtein EngineeringTransaminasesGreen Chemistry TechnologyMolecular Docking SimulationStereoisomerismSubstrate SpecificityAminesTransaminasesAI-assisted protein engineeringamine transaminasebiocatalysischiral amines

Identifiers

PMID41154664
PMCPMC12564524

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.