Evidence map›Paper›PMID 41154648›Full record

ArticleBiomolecules2025

Effects of HDL Structure and Function in Peripheral Artery Disease.

Yu-Huang Liao, Semon Wu, Yu-Lin Ko, Ming-Sheng Teng

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yu-Huang LiaoDivision of Endocrinology and Metabolism, Department of Internal Medicine, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei City 231016, Taiwan.ORCID 0000-0003-1306-1200
Semon WuDepartment of Life Science, Chinese Culture University, Taipei 111396, Taiwan.
Yu-Lin KoDepartment of Research, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei City 231016, Taiwan.ORCID 0000-0002-8218-6827
Ming-Sheng TengDivision of Endocrinology and Metabolism, Department of Internal Medicine, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei City 231016, Taiwan.ORCID 0000-0003-4140-5699

Funding

Ministry of Science and Technology MOST 109-2314-B-303-021-MY2, MOST 111-2314-B-303-002, TCRD-TPE-MOST-111-14Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation TCRD-TPE-111-12(1/2), TCRD-TPE-111-12(2/2), TCRD-TPE-113-06(1/2), TCRD-TPE-NCU-113-07
6 · The paper itself

Abstract

The structure and function of high-density lipoprotein (HDL), rather than its concentration, are more important factors in determining HDL activity. HDL particles (HDL-P) are heterogeneous in their composition, size, and antioxidative function. We investigated the levels of HDL subfractions and oxidized high-density lipoprotein (Ox-HDL) and validated their correlation with genetic determinants underlying peripheral artery disease (PAD). We recruited a PAD population stratified by claudication severity (group I) and critical limb ischemia (group II) according to the Rutherford classification. We found that the level of Ox-HDL was significantly increased with Rutherford classification (group II;

Indexed as

Lipoproteins, HDLPeripheral Arterial DiseaseAgedCholesterol, HDLFemaleHumansMaleMiddle AgedPolymorphism, Single NucleotideCholesterol, HDLLipoproteins, HDLHDL subfractionsOx-HDLPADSNP

Identifiers

PMID41154648
PMCPMC12564848

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.