Asiatic Acid from

Chaiwat Monmai, Sahachai Sabuakham, Wachirachai Pabuprapap, Waraluck Chaichompoo, Apichart Suksamrarn, Panupong Mahalapbutr

Abstract read

PubMed Full text at PMC Publisher

In one paragraph

Article in Biomolecules, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chaiwat MonmaiDepartment of Biochemistry, and Center for Translational Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.ORCID 0000-0002-9267-3047

Sahachai SabuakhamSchool of Biomolecular Science and Engineering, Vidyasirimedhi Institute of Science and Technology, Rayong 21210, Thailand.ORCID 0009-0001-3390-8838

Wachirachai PabuprapapDepartment of Chemistry, and Center of Excellence for Innovation in Chemistry, Faculty of Science, Ramkhamhaeng University, Bangkok 10240, Thailand.ORCID 0000-0001-6445-7550

Waraluck ChaichompooDepartment of Chemistry, and Center of Excellence for Innovation in Chemistry, Faculty of Science, Ramkhamhaeng University, Bangkok 10240, Thailand.ORCID 0000-0002-6359-5828

Apichart SuksamrarnDepartment of Chemistry, and Center of Excellence for Innovation in Chemistry, Faculty of Science, Ramkhamhaeng University, Bangkok 10240, Thailand.ORCID 0000-0001-8919-3555

Panupong MahalapbutrDepartment of Biochemistry, and Center for Translational Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.ORCID 0000-0003-4389-334X

Funding

Fundamental Fund of Khon Kaen UniversityPost Doctoral Training Program for Frontier Research from Khon Kaen University PD2568-08

6 · The paper itself

Abstract

Lung cancer is a leading cause of cancer mortality worldwide. Targeted therapies with epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) represent a significant advance in the management of lung cancer. However, their long-term efficacy is often limited by acquired resistance, particularly due to the T790M mutation, highlighting the need for novel EGFR-TKIs. Although compounds derived from

Indexed as

Antineoplastic AgentsCarcinoma, Non-Small-Cell LungCentellaLung NeoplasmsPentacyclic TriterpenesProtein Kinase InhibitorsA549 CellsApoptosisCell Line, TumorCell ProliferationErbB ReceptorsHumansMolecular Docking SimulationMutationTriterpenesTyrosine Kinase InhibitorsAntineoplastic Agentsasiatic acidasiaticosideEGFR protein, humanErbB ReceptorsPentacyclic TriterpenesProtein Kinase InhibitorsTriterpenesTyrosine Kinase InhibitorsanticancerCentella asiaticaEGFRmolecular dockingNSCLCpentacyclic triterpenoid

Identifiers

PMID41154639

DOI10.3390/biom15101410

PMCPMC12563520

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.