Evidence map›Paper›PMID 41154417›Full record

ArticleCancers2025

Increased EGFR/HER2 Pathway Activation Contributes to Skin Tumorigenesis in

Laura R Purkey, Stefania Mehedincu, Charles Irvine, Raelyn Akdag, Megan Little, W Wade Kothmann, Katharine Rus, Erin Greenberg, Neil Shady, Kathleen DeCicco-Skinner

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Laura R PurkeyDepartment of Biology, American University, Washington, DC 20016, USA.
Stefania MehedincuDepartment of Biology, American University, Washington, DC 20016, USA.
Charles IrvineDepartment of Biology, American University, Washington, DC 20016, USA.
Raelyn AkdagDepartment of Biology, American University, Washington, DC 20016, USA.
Megan LittleDepartment of Biology, American University, Washington, DC 20016, USA.
W Wade KothmannDepartment of Biochemistry and Molecular & Cellular Biology, Georgetown University, Washington, DC 20057, USA.
Katharine RusDepartment of Biology, American University, Washington, DC 20016, USA.
Erin GreenbergDepartment of Biology, American University, Washington, DC 20016, USA.
Neil ShadyDepartment of Biology, American University, Washington, DC 20016, USA.
Kathleen DeCicco-SkinnerDepartment of Biology, American University, Washington, DC 20016, USA.ORCID 0000-0002-0256-5609

Funding

Mellon Grant, American University N/A
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

cSCCEGFRErbB2HER2MAP3K8miR-205miR-21Tpl2

Identifiers

PMID41154417
PMCPMC12563468

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.