Natural Deep Eutectic Solvents Enhance the Bioavailability and Antioxidant Activity of Oleanolic Acid in Self-Constructed Pickering High Internal Phase Emulsions.

Jie Yu, Chenjia Li, Qin Zhang, Benyang Li, Chaoxi Zeng

Abstract read

In one paragraph

Article in Foods (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Evaluating the suitability of six hydrophobic natural eutectic solvents as the internal phase in a cosmetic cream formulation.International journal of cosmetic science · 2026
Article

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jie YuDepartment of Food Science and Technology, College of Food Science and Technology, Hunan Agricultural University, No. 1 Nongda Road, Furong District, Changsha 410128, China.

Chenjia LiDepartment of Food Science and Technology, College of Food Science and Technology, Hunan Agricultural University, No. 1 Nongda Road, Furong District, Changsha 410128, China.

Qin ZhangDepartment of Food Science and Technology, College of Food Science and Technology, Hunan Agricultural University, No. 1 Nongda Road, Furong District, Changsha 410128, China.

Benyang LiXiangya School of Public Health, Central South University, 172 Tongzipo Road, Changsha 410013, China.

Chaoxi ZengXiangya School of Public Health, Central South University, 172 Tongzipo Road, Changsha 410013, China.

Funding

Key Research and Development Project of Hunan Province, China 2022NK2033the Natural Science Foundation of Hunan Province, China 2021JJ30321the Natural Science Foundation of Hunan Province, China 2024JJ5185

6 · The paper itself

Abstract

Oleanolic acid (OA)-stabilized water-in-oil Pickering high internal phase emulsions (HIPEs), using natural deep eutectic solvents (NADESs) as the internal phase (HIPE-NADES), were developed to enhance OA bioavailability. Three kinds of NADESs (proline: sorbitol (1:1), proline: glucose (1:1), and proline: glucose (5:3)) were selected, and HIPEs with pure water as the internal phase were used as the control group. In vitro digestion and Caco-2 models showed that HIPE-NADES significantly improved OA bioaccessibility via enhanced stability and solubility. Crucially, OA bioavailability reached 16.20-19.10%, markedly surpassing controls (

Indexed as

antioxidantbioavailabilityhigh internal phase emulsionnatural deep eutectic solventoleanolic acid

Identifiers

PMID41154106

DOI10.3390/foods14203568

PMCPMC12562568

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LicenceCC BY

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.