Evidence map›Paper›PMID 41154028›Full record

ArticleFoods (Basel, Switzerland)2025

Mao Jian Black Tea Ethanol Extract Alleviates Alcoholic Liver Injury in Mice via Regulation of the PI3K/Akt/NF-κB Signaling Pathway.

Lei Wu, Xiaomeng Guo, Yao Niu, Siyu Li, Shiyu Jiang, Xinyuan Wang, Yukang Gao, Shan Zhang, Litao Zhou, Lingdan Yang and 2 more

Abstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Lei WuCollege of Life Sciences, Shanxi Agricultural University, Jinzhong 030801, China.ORCID 0000-0002-1087-9034
Xiaomeng GuoModern Research Center for Traditional Chinese Medicine, Shanxi University, Taiyuan 030006, China.
Yao NiuModern Research Center for Traditional Chinese Medicine, Shanxi University, Taiyuan 030006, China.ORCID 0009-0004-2394-6525
Siyu LiCollege of Life Sciences, Shanxi Agricultural University, Jinzhong 030801, China.
Shiyu JiangCollege of Life Sciences, Shanxi Agricultural University, Jinzhong 030801, China.
Xinyuan WangCollege of Life Sciences, Shanxi Agricultural University, Jinzhong 030801, China.
Yukang GaoCollege of Life Sciences, Shanxi Agricultural University, Jinzhong 030801, China.
Shan ZhangCollege of Life Sciences, Shanxi Agricultural University, Jinzhong 030801, China.
Litao ZhouCollege of Life Sciences, Shanxi Agricultural University, Jinzhong 030801, China.
Lingdan YangCollege of Life Sciences, Shanxi Agricultural University, Jinzhong 030801, China.
Zian GaoCollege of Life Sciences, Shanxi Agricultural University, Jinzhong 030801, China.
Yuqing YangCollege of Life Sciences, Shanxi Agricultural University, Jinzhong 030801, China.

Funding

Introduction of talent research start-up fund by Shanxi Agricultural University 2023BQ102
6 · The paper itself

Abstract

This study investigates the protective effects and underlying mechanisms of Mao Jian Black tea ethanol extract (MJBT_EE) on a mouse model of acute alcohol-induced liver injury (ALI). The animal model was established using the NIAAA method, and C57BL/6 mice were divided into the following groups: negative control group (NC), model control group (MG), silibinin positive control group (SL, 54 mg/kg), and MJBT_EE high- and low-dose groups (40 mg/mL, 20 mg/mL). The results showed that, compared to the MG, MJBT_EE significantly reduced serum levels of ALT, AST, TC, TG, LDL-C, TBIL, ALP and inflammatory cytokines IL-6, TNF-α, and IL-1β (

Indexed as

alcohol-induced liver injuryanti-inflammatoryantioxidantlipid metabolismPI3K/Akt/NF-κB pathway

Identifiers

PMID41154028
PMCPMC12563102

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.