Evidence map›Paper›PMID 41153970›Full record

ArticleAnimals : an open access journal from MDPI2025

Primary Uterine Inertia (PUI) in Dogs Is Associated with Impaired Placental Availability of Factors Involved in the Parturition Cascade.

Marianne Steiner, Gerhard Schuler, Bianca L Frehner, Iris M Reichler, Sandra Goericke-Pesch, Orsolya Balogh, Miguel Tavares Pereira, Mariusz P Kowalewski

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Uterine Dysfunctions in Non-Pregnant and Pregnant Small Animals.Reproduction in domestic animals = Zuchthygiene · 2026
    Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Marianne SteinerInstitute of Veterinary Anatomy, Vetsuisse Faculty, University of Zurich, CH-8057 Zurich, Switzerland.
Gerhard SchulerClinic for Obstetrics, Gynecology and Andrology of Large and Small Animals, Justus-Liebig-University, 35392 Giessen, Germany.ORCID 0000-0002-9412-3743
Bianca L FrehnerClinic for Reproductive Medicine, Vetsuisse Faculty, University of Zurich, CH-8057 Zurich, Switzerland.ORCID 0000-0001-6666-0130
Iris M ReichlerClinic for Reproductive Medicine, Vetsuisse Faculty, University of Zurich, CH-8057 Zurich, Switzerland.ORCID 0000-0001-7762-1217
Sandra Goericke-PeschUnit for Reproductive Medicine, Clinic for Small Animals, University of Veterinary Medicine Hannover, 30559 Hannover, Germany.ORCID 0000-0002-4327-9780
Orsolya BaloghClinical Sciences, Virginia-Maryland College of Veterinary Medicine, Blacksburg, VA 24061, USA.ORCID 0000-0003-0939-2859
Miguel Tavares PereiraInstitute of Veterinary Anatomy, Vetsuisse Faculty, University of Zurich, CH-8057 Zurich, Switzerland.ORCID 0000-0002-0537-5675
Mariusz P KowalewskiInstitute of Veterinary Anatomy, Vetsuisse Faculty, University of Zurich, CH-8057 Zurich, Switzerland.ORCID 0000-0002-4565-7714

Funding

The present work was financially supported with funds from the Institute of Veterinary Anatomy, Vetsuisse Faculty, University of Zurich. N/A
6 · The paper itself

Abstract

The canine parturition cascade involves decreased placental progesterone (P4) signaling mediated through its nuclear receptor PGR in decidual cells, leading to increased trophoblast production of PGF2α that promotes luteolysis, placentolysis, and myometrial contractility. A local role for glucocorticoids in initiating parturition through increased placental availability of cortisol and glucocorticoid receptor (

Indexed as

dog (Canis lupus familiaris)parturition cascadeplacentaprimary uterine inertia (PUI)progesterone signaling

Identifiers

PMID41153970
PMCPMC12561314

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.