Evidence map›Paper›PMID 41153942›Full record

ArticleAnimals : an open access journal from MDPI2025

Outbreak of Respiratory Disease Due to Bovine Respiratory Syncytial Virus with Concomitant Infections by

João Henrique Perotta, Isabela Vaz Silva, Maria Constanza Rodriguez, Mara Eliza Gasino Joineau, Marcel Kruchelski Tschá, Renato Silva de Sousa, Alais Maria Dall Agnol, Flávia Helena Pereira Silva, Sébastien Buczinski, Selwyn Arlington Headley and 1 more

Abstract readCase Reports
In one paragraph

Article in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

João Henrique PerottaDepartment of Veterinary Medicine, Federal University of Paraná, Rua dos Funcionários, 1540, Curitiba 80035-050, Paraná, Brazil.ORCID 0000-0001-8831-7376
Isabela Vaz SilvaDepartment of Veterinary Medicine, Federal University of Paraná, Rua dos Funcionários, 1540, Curitiba 80035-050, Paraná, Brazil.ORCID 0000-0002-2000-8769
Maria Constanza RodriguezMarcos Enrietti Diagnostic Center, Paraná Agricultural Defense Agency, Rua Jaime Balão, 575, Curitiba 80040-340, Paraná, Brazil.ORCID 0000-0002-1608-3360
Mara Eliza Gasino JoineauMarcos Enrietti Diagnostic Center, Paraná Agricultural Defense Agency, Rua Jaime Balão, 575, Curitiba 80040-340, Paraná, Brazil.ORCID 0009-0009-0101-2605
Marcel Kruchelski TscháInstituto de Biologia Molecular do Paraná (IBPM), Rua Professor Algacyr Munhoz Mader, 3775, Curitiba 81350-010, Paraná, Brazil.ORCID 0000-0002-5882-0007
Renato Silva de SousaDepartment of Veterinary Medicine, Federal University of Paraná, Rua dos Funcionários, 1540, Curitiba 80035-050, Paraná, Brazil.ORCID 0000-0002-6491-9302
Alais Maria Dall AgnolLaboratory of Animal Virology, Department of Veterinary Preventive Medicine, Universidade Estadual de Londrina, Rodovia Celso Garcia Cid, PR 445 Km 380, Londrina 86057-970, Paraná, Brazil.ORCID 0000-0002-0420-820X
Flávia Helena Pereira SilvaLaboratory of Animal Pathology, Department of Veterinary Preventive Medicine, Universidade Estadual de Londrina, Rodovia Celso Garcia Cid, PR 445 Km 380, Londrina 86057-970, Paraná, Brazil.ORCID 0000-0002-8371-7992
Sébastien BuczinskiDépartement des Sciences Cliniques, Faculté de Médecine Vétérinaire, Université de Montréal, St-Hyacinthe, QC J2S 2M2, Canada.ORCID 0000-0002-8460-4885
Selwyn Arlington HeadleyLaboratory of Animal Pathology, Department of Veterinary Preventive Medicine, Universidade Estadual de Londrina, Rodovia Celso Garcia Cid, PR 445 Km 380, Londrina 86057-970, Paraná, Brazil.ORCID 0000-0002-1614-0185
Ivan Roque de Barros FilhoDepartment of Veterinary Medicine, Federal University of Paraná, Rua dos Funcionários, 1540, Curitiba 80035-050, Paraná, Brazil.ORCID 0000-0002-0056-9358

Funding

National Council for Scientific and Technological Development 310259/2021-5
6 · The paper itself

Abstract

Although bovine respiratory syncytial virus (BRSV) is a key contributor to bovine respiratory disease (BRD) worldwide, there are few detailed reports of BRSV-related outbreaks in Brazil. This study describes the clinical, pathological, immunohistochemical (IHC), and molecular findings from a BRD outbreak in adult dairy cows from Southern Brazil. The affected cattle had dyspnea, nasal discharge, and coughing. One cow died, and samples were collected for diagnosis. Histopathology revealed interstitial pneumonia with multinucleated giant cells. IHC identified BRSV antigens in pulmonary tissue. A multiplex real-time PCR identified BRSV,

Indexed as

bovine respiratory diseasediagnostic immunohistochemistryinterstitial pneumoniamolecular identificationmultiplex qPCRnon-vaccinated dairy cattle

Identifiers

PMID41153942
PMCPMC12561571

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.