Evidence map›Paper›PMID 41153729›Full record

ArticleBiomedicines2025

Developmentally Regulated CYP2E1 Expression Is Associated with a Fetal Pulmonary Transcriptional Response to Maternal Acetaminophen Exposure.

Emma M Golden, Zhuowei Li, Lijun Zheng, Mack Solar, Maya R Grayck, Nicole Talaba, David J McCulley, David J Orlicky, Clyde J Wright

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedicines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. TLR9-mediated innate immune signaling contributes to acetaminophen-induced injury in the developing lung.American journal of physiology. Lung cellular and molecular physiology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Emma M GoldenSection of Neonatology, Department of Pediatrics, University of Colorado School of Medicine, Aurora, CO 80045, USA.ORCID 0000-0002-3887-8252
Zhuowei LiDivision of Neonatology, Department of Pediatrics, University of California, San Diego, CA 94143, USA.ORCID 0009-0004-6901-6497
Lijun ZhengSection of Neonatology, Department of Pediatrics, University of Colorado School of Medicine, Aurora, CO 80045, USA.
Mack SolarSection of Neonatology, Department of Pediatrics, University of Colorado School of Medicine, Aurora, CO 80045, USA.
Maya R GrayckSection of Neonatology, Department of Pediatrics, University of Colorado School of Medicine, Aurora, CO 80045, USA.
Nicole TalabaDivision of Neonatology, Department of Pediatrics, University of California, San Diego, CA 94143, USA.
David J McCulleyDivision of Neonatology, Department of Pediatrics, University of California, San Diego, CA 94143, USA.ORCID 0000-0001-8336-363X
David J OrlickyDepartment of Pathology, University of Colorado Anschutz School of Medicine, Aurora, CO 80045, USA.ORCID 0000-0002-0417-1400
Clyde J WrightSection of Neonatology, Department of Pediatrics, University of Colorado School of Medicine, Aurora, CO 80045, USA.ORCID 0000-0002-8449-5631

Funding

Research Supplement to Promote Diversity in Health Related Research: Pulmonary implications ofperinatal acetaminophen exposureR01HD107700 · NICHD · UNIVERSITY OF COLORADO DENVER · PI Clyde Jason Wright · 2022 to 2026
$2.2M
GENETIC AND DEVELOPMENTAL MECHANISMS OF CONGENITAL DIAPHRAGMATIC HERNIAR01HL146859 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI MCCULLEY, DAVID J · 2019 to 2023
$2.0M
NHLBI NIH HHS R01 HL146859NHLBI NIH HHS R01HL146859NICHD NIH HHS R01 HD107700NIH HHS R01HD107700
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

acetaminophenCYP2E1fetallung injuryparacetamolprenatal

Identifiers

PMID41153729
PMCPMC12561974

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.