Evidence map›Paper›PMID 41153683›Full record

ArticleBiomedicines2025

Intranasal 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) Administration Hampered Contractile Response of Dopamine in Isolated Rat Ileum.

Ana Silva, Sofia Viana, Inês Pita, Cristina Lemos, Filipe C Matheus, Lina Carvalho, Carlos A Fontes Ribeiro, Rui D Prediger, Frederico C Pereira, Sónia Silva

Abstract read
In one paragraph

Article in Biomedicines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ana SilvaInstitute of Pharmacology and Experimental Therapeutics, Faculty of Medicine, University of Coimbra, 3000-548 Coimbra, Portugal.
Sofia VianaInstitute of Pharmacology and Experimental Therapeutics, Faculty of Medicine, University of Coimbra, 3000-548 Coimbra, Portugal.ORCID 0000-0002-1316-1319
Inês PitaInstitute of Pharmacology and Experimental Therapeutics, Faculty of Medicine, University of Coimbra, 3000-548 Coimbra, Portugal.
Cristina LemosCentre for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, 3004-504 Coimbra, Portugal.
Filipe C MatheusDepartment of Pharmaceutical Sciences, Federal University of Santa Catarina (UFSC), Florianópolis 88040-900, Brazil.ORCID 0000-0003-3525-5954
Lina CarvalhoInstitute of Anatomical and Molecular Pathology, University of Coimbra, 3004-504 Coimbra, Portugal.
Carlos A Fontes RibeiroInstitute of Pharmacology and Experimental Therapeutics, Faculty of Medicine, University of Coimbra, 3000-548 Coimbra, Portugal.ORCID 0000-0002-9707-4895
Rui D PredigerDepartment of Pharmacology, Center of Biological Sciences, Federal University of Santa Catarina (UFSC), Florianópolis 88040-900, Brazil.ORCID 0000-0002-7547-6463
Frederico C PereiraInstitute of Pharmacology and Experimental Therapeutics, Faculty of Medicine, University of Coimbra, 3000-548 Coimbra, Portugal.ORCID 0000-0002-9381-3320
Sónia SilvaCoimbra Institute for Clinical and Biomedical Research (iCBR), Faculty of Medicine, University of Coimbra, 3000-548 Coimbra, Portugal.ORCID 0000-0001-9869-8651

Funding

Portuguese Foundation for Science and Technology UIDB/04539/2020 and UIDP/04539/2020 (CIBB)
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

D2-like receptorsdopamineenteroglial cellsGI dysfunctionintranasal MPTPParkinson’s disease

Identifiers

PMID41153683
PMCPMC12562183

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.