Evidence map›Paper›PMID 41153614›Full record

ArticleBiomedicines2025

Monocyte-Derived Macrophages Expressing Dopamine D2-Subtype Receptors Drive Alcohol Effects on Mesolimbic Neurons and Microglia.

Christina A Nelson, J Daniel Obray, Travis J Clarke, James N Brundage, Ryan J Folsom, Carlos M Moreno, Pacen E Williams, Lauren H Ford, Sandra Hope, K Scott Weber and 3 more

Abstract read
In one paragraph

Article in Biomedicines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Christina A NelsonDepartment of Psychology and Center for Neuroscience, Brigham Young University, Provo, UT 84602, USA.
J Daniel ObrayDepartment of Psychology and Center for Neuroscience, Brigham Young University, Provo, UT 84602, USA.ORCID 0000-0001-7526-4869
Travis J ClarkeDepartment of Psychology and Center for Neuroscience, Brigham Young University, Provo, UT 84602, USA.
James N BrundageDepartment of Psychology and Center for Neuroscience, Brigham Young University, Provo, UT 84602, USA.
Ryan J FolsomDepartment of Psychology and Center for Neuroscience, Brigham Young University, Provo, UT 84602, USA.
Carlos M MorenoDepartment of Microbiology and Molecular Biology, Brigham Young University, Provo, UT 84602, USA.ORCID 0000-0003-1688-4990
Pacen E WilliamsDepartment of Psychology and Center for Neuroscience, Brigham Young University, Provo, UT 84602, USA.
Lauren H FordDepartment of Psychology and Center for Neuroscience, Brigham Young University, Provo, UT 84602, USA.ORCID 0009-0009-2136-9070
Sandra HopeDepartment of Microbiology and Molecular Biology, Brigham Young University, Provo, UT 84602, USA.ORCID 0000-0002-9060-0485
K Scott WeberDepartment of Microbiology and Molecular Biology, Brigham Young University, Provo, UT 84602, USA.ORCID 0000-0003-3688-2191
Kyle B BillsDepartment of Research, Noorda College of Osteopathic Medicine, Provo, UT 84606, USA.
Jordan T YorgasonDepartment of Cellular Biology and Physiology, Brigham Young University, Provo, UT 84602, USA.
Scott C SteffensenDepartment of Psychology and Center for Neuroscience, Brigham Young University, Provo, UT 84602, USA.ORCID 0000-0001-6463-8861

Funding

Nicotine and Alcohol Co-DependenceR01DA035958 · NIDA · BRIGHAM YOUNG UNIVERSITY · PI STEFFENSEN, SCOTT C · 2014 to 2018
$2.0M
Neuroplasticity with alcohol dependenceR01AA020919 · NIAAA · BRIGHAM YOUNG UNIVERSITY · PI STEFFENSEN, SCOTT C · 2012 to 2016
$1.5M
Neuroimmune mechanisms of alcohol rewardR01AA030577 · NIAAA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Jordan Thomas Yorgason · 2023 to 2026
$1.3M
Amelioration of opioid withdrawal-induced anxiety and craving with heterodyned whole body vibrationR41DA053083 · NIDA · PHOTOPHARMICS, INC. · PI ADAMS, DANIEL NATHAN, STEFFENSEN, SCOTT C · 2021 to 2021
$320k
Amelioration of opioid use disorder with heterodyned whole body vibrationR42DA060644 · NIDA · PHOTOPHARMICS, INC. · PI ADAMS, DANIEL NATHAN, STEFFENSEN, SCOTT C · 2024 to 2024
$319k
NIAAA NIH HHS R01 AA020919NIAAA NIH HHS R01 AA030577NIDA NIH HHS R01 DA035958NIDA NIH HHS R41 DA053083NIDA NIH HHS R42 DA060644PHS NIH AA020919PHS NIH AA030577PHS NIH DA035598PHS NIH DA053083PHS NIH DA60644
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

alcoholcytokinesdopamine 2 receptorsmacrophagemicrogliamonocytesneuroimmunomodulationneuroinflammation

Identifiers

PMID41153614
PMCPMC12561246

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.