Evidence map›Paper›PMID 41153417›Full record

ReviewGenes2025

How Close Are We to Achieving Durable and Efficacious Gene Therapy for Hemophilia A and B?

Patrycja Sosnowska-Sienkiewicz, Danuta Januszkiewicz-Lewandowska

Abstract readReview
In one paragraph

Review in Genes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Patrycja Sosnowska-SienkiewiczDepartment of Pediatric Surgery, Medical University of Warsaw, Żwirki i Wigury 63A Street, 02-091 Warsaw, Poland.ORCID 0000-0003-4714-6501
Danuta Januszkiewicz-LewandowskaDepartment of Pediatric Oncology, Hematology and Transplantology, Poznan University of Medical Sciences, ul. Fredry 10, 61-701 Poznan, Poland.ORCID 0000-0003-2332-2750

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hemophilia, an X-linked recessive bleeding disorder, results from mutations in the

Indexed as

Genetic TherapyHemophilia AHemophilia BAnimalsFactor IXFactor VIIIGene EditingGenetic VectorsGene Transfer TechniquesHumansFactor IXFactor VIIIfactor IX deficiencyfactor VIII deficiencygene therapyhemophilia Ahemophilia B

Identifiers

PMID41153417
PMCPMC12563086

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.