Evidence map›Paper›PMID 41153380›Full record

ArticleGenes2025

Lipid Metabolism and Circadian Regulation in Wing Polyphenism of

Yan Zhang, Tao Zhang, Jianwu Mao, Shenhang Cheng

Abstract read
In one paragraph

Article in Genes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yan ZhangDepartment of Biological Science and Technology, Jinzhong University, Jinzhong 030619, China.
Tao ZhangSchool of Synthetic Biology, Shanxi University, Taiyuan 030006, China.
Jianwu MaoSchool of Synthetic Biology, Shanxi University, Taiyuan 030006, China.
Shenhang ChengSchool of Synthetic Biology, Shanxi University, Taiyuan 030006, China.

Funding

Basic Research Program (Free Exploration Category) of Shanxi Provincial Department of Science and Technology No. 202403021222343‌China Postdoctoral Science Foundation No.113521040National Natural Science Foundation of China No. 32202341
6 · The paper itself

Abstract

BACKGROUND/

objectivesThe bird cherry-oat aphid,

methodsTo identify potential RNAi targets that could specifically disrupt the migratory winged morph, we conducted a comparative transcriptomic analysis of adult aphids. Differentially expressed genes (DEGs) were identified, annotated for their functions, and analyzed for their involvement in metabolic pathways.

resultsSignificant differences were observed in 121 genes between morphs: 13 were upregulated in the winged morph, while 108 were downregulated. Most DEGs were enriched in lipid metabolism and circadian rhythm pathways, suggesting that wing polymorphism may be adaptively linked to energy resource allocation strategies.

conclusionsThis study firstly reveals the adult-stage-specific regulatory roles of lipid metabolism and circadian rhythm pathways in wing polyphenism, identifying six candidate genes (

Indexed as

AphidsCircadian RhythmLipid MetabolismTranscriptomeWings, AnimalAnimalsGene Expression ProfilingInsect ProteinsInsect Proteinscircadian rhythmenergy allocationlipid metabolismRhopalosiphum padiRNAi-based biocontroltranscriptomicswing polyphenism

Identifiers

PMID41153380
PMCPMC12564907

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.