Evidence map›Paper›PMID 41153377›Full record

ArticleGenes2025

Interactions Between Monocarboxylate Transporter

Ewelina Maculewicz, Andrzej Mastalerz, Anna Mróz, Monika Johne, Katarzyna Krawczak-Wójcik, Agata Pabin, Aleksandra Garbacz, Katarzyna Komar, Myosotis Massidda, Petr Stastny and 1 more

Abstract read
In one paragraph

Article in Genes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ewelina MaculewiczFaculty of Physical Education, Jozef Pilsudski University of Physical Education in Warsaw, 00-968 Warsaw, Poland.ORCID 0000-0002-3122-3085
Andrzej MastalerzFaculty of Physical Education, Jozef Pilsudski University of Physical Education in Warsaw, 00-968 Warsaw, Poland.
Anna MrózFaculty of Physical Education, Jozef Pilsudski University of Physical Education in Warsaw, 00-968 Warsaw, Poland.ORCID 0000-0001-7169-5493
Monika JohneFaculty of Physical Education, Jozef Pilsudski University of Physical Education in Warsaw, 00-968 Warsaw, Poland.ORCID 0000-0002-7066-8909
Katarzyna Krawczak-WójcikFaculty of Physical Education, Jozef Pilsudski University of Physical Education in Warsaw, 00-968 Warsaw, Poland.ORCID 0000-0001-7557-8059
Agata PabinDepartment of Laboratory Diagnostics, Military Institute of Aviation Medicine, 01-755 Warsaw, Poland.
Aleksandra GarbaczFaculty of Animal Genetics and Conservation, Warsaw University of Life Sciences, 02-787 Warsaw, Poland.ORCID 0000-0003-0050-7891
Katarzyna KomarDepartment of Laboratory Diagnostics, Military Institute of Aviation Medicine, 01-755 Warsaw, Poland.ORCID 0009-0002-0636-2961
Myosotis MassiddaDepartment of Medical Sciences and Public Health, University of Cagliari, 72-09124 Cagliari, Italy.ORCID 0000-0001-5726-4435
Petr StastnyFaculty of Physical Education and Sport, Charles University, 162-52 Prague, Czech Republic.ORCID 0000-0003-2841-374X
Aleksandra BojarczukFaculty of Physical Education, Gdansk University of Physical Education and Sport, 80-336 Gdansk, Poland.

Funding

Ministry of Science and Higher Education UPB No. 12National Science Centre MINIATURA 6
6 · The paper itself

Abstract

BACKGROUND/

objectivesLactate (LA) is a key metabolite in exercise metabolism, transported across cell membranes by monocarboxylate transporters (MCTs). Although genetic variation in

methods337 Polish and Czech males (elite athletes, sub-elite competitors, physically active controls) performed two maximal Wingate tests. Buccal swabs were collected for DNA extraction and single nucleotide polymorphism (SNP) genotyping. LA was assessed before and after the tests.

resultsFive variants (rs3789592, rs7556664, rs7169, rs1049434, rs6537765) remained significantly associated with LA measured 30 min after the second Wingate (LA30') and delta clearance capacity (DCC) in elites (codominant and recessive models:

conclusionsThe results suggest that

Indexed as

ExerciseLactic AcidMonocarboxylic Acid TransportersPolymorphism, Single NucleotideSymportersAdultAthletesCross-Sectional StudiesHumansKineticsMaleMonocarboxylate Transport Protein 1Young AdultLactic AcidMonocarboxylate Transport Protein 1Monocarboxylic Acid TransportersSymportersgenotypelactate kineticsMCT1polymorphismsWingate

Identifiers

PMID41153377
PMCPMC12564665

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.