ArticleBMC research notes2025
Stress-reducing effect of laughter in live comedy performance from salivary α-amylase and salivary oxytocin.
Article in BMC research notes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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4 authors.
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Abstract
objectiveLaughter is recognized for its potential to alleviate stress. Salivary α-amylase (sAA) is a well-known stress marker; however, the relationship between salivary oxytocin (sOXT) and stress reducing effects by laughter remains unclear. We previously determined the relationship between laughter and optimism, anxiety, and amylase; In this study, the relationship between spontaneous laughter and stress reduction during a live comedy performance (LCP) was investigated by measuring sAA and sOXT activity before and after the performance.
resultsPre-LCP sAA was significantly positively correlated with a decreasing post-sAA/pre-sAA ratio; the scale of this effect was age dependent. Furthermore, participants who reported laughing 'several times a month' showed the highest value in the post-/pre-LCP sAA ratio. In contrast, those who reported laughing 'many times a day' had the lowest value. Contrary to our expectations, sOXT levels were significantly lower in post-LCP samples than they were in pre-LCP samples. This is thought to be because OXT has an anti-stress hormone effect, and stress was reduced after LCP, resulting in a decrease in oxytocin secretion. Our findings offer new insight into the stress-reducing effects of laughter.
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