Evidence map›Paper›PMID 41152988›Full record

ArticleJournal of orthopaedic surgery and research2025

Proximal fibular partial excision delays medial joint space narrowing of the medial tibiofemoral joint.

Yi Li, Meng Zou, Juan Zheng, Qiang Huang, Xin Duan, Haibo Si

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Article in Journal of orthopaedic surgery and research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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6 authors.

Yi Li *Department of Orthopedics, West China Hospital, Sichuan University, 37# Guoxue Road, Chengdu, 610041, China.
Meng Zou *Department of Radiology, Chengdu Shangjin Nanfu Hospital, West China Hospital, Sichuan University, Chengdu, 611743, China.
Juan ZhengCollege of Computer Science, West China Hospital, Sichuan University, Chengdu, 610041, China.
Qiang HuangDepartment of Orthopedics, West China Hospital, Sichuan University, 37# Guoxue Road, Chengdu, 610041, China. 1714610774@qq.com.
Xin DuanDepartment of Orthopedics, West China Hospital, Sichuan University, 37# Guoxue Road, Chengdu, 610041, China. dxbaal@hotmail.com.
Haibo SiDepartment of Orthopedics, West China Hospital, Sichuan University, 37# Guoxue Road, Chengdu, 610041, China. sihaibo@wchscu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundProximal fibular partial excision (PFPE) is a novel treatment for medial compartment knee osteoarthritis (KOA), but its benefits, especially radiological benefits, are still controversial. This retrospective cohort study aims to investigate the osteoarthritic progression in medial tibiofemoral congruence and joint space width (JSW) following PFPE.

methodsThe patients with medial compartment KOA who accepted PFPE or nonsurgical treatment were retrospectively enrolled. Preoperative/baseline, postoperative, and 5-years follow-up X-ray radiographs were collected. A novel self-designed curve-fitting algorithm was created and the medial tibiofemoral congruence and JSW were calculated and compiled semi-automatically. A total of 77 patients were initially enrolled in this study, and those who completed follow-up after PFPE were selected for 1:1 propensity score matching (PSM) with control patients. Variables adjusted in PSM included preoperative/baseline age, gender, BMI, side, medial tibiofemoral congruence, and JSW (including mean, maximum, and minimum values), resulting in 30 patients in each group. Comparisons between the PFPE group and control group were performed both before and after PSM.

resultsA total of 77 PFPE knees and 112 control knees were identified from a comprehensive 5-years retrospective study. In the PFPE knees, the postoperative mean and minimum JSW significantly increased compared with the preoperative values (mean: 4.634 vs. 4.457, p = 0.031; minimum: 4.012 vs. 3.836, p = 0.031, respectively). Thirty-three PFPE knees completed a 5-years follow-up, and no statistical difference in the congruence and JSW was observed between preoperative and follow-up outcomes (all p > 0.05). In the 112 control knees, the JSW significantly decreased at the 5-years follow-up compared to the baseline conditions (all p < 0.01). After PSM, 30 knees in each group were selected, and significantly higher JSW was observed in the PFPE group at the 5-years follow-up (mean: 4.350 vs. 3.650, p = 0.007; maximum: 5.740 vs. 5.095, p = 0.046; minimum: 3.739 vs. 2.963, p = 0.003, respectively).

conclusionsPFPE delays the medial joint space narrowing of the medial tibiofemoral joint at a 5-years follow-up, providing new evidence for the long-term radiological benefits of PFPE. Future prospective and large sample studies are still needed to objectively evaluate the advantages and disadvantages of PFPE. LEVEL OF EVIDENCE: Level III, therapeutic study.

Indexed as

FibulaKnee JointOsteoarthritis, KneeTibiaAgedCohort StudiesDisease ProgressionFemaleFollow-Up StudiesHumansMaleMiddle AgedRadiographyRetrospective StudiesTibiofemoral JointJoint space widthKnee-sparing surgeryMedial compartment knee osteoarthritisProximal fibular partial excisionTibiofemoral congruence

Identifiers

PMID41152988
PMCPMC12560433

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.