SynthesisWorld journal of surgical oncology2025
Incidence of flap-related complications in the oral reconstruction area after free flap reconstruction in patients with oral cancer.
Synthesis in World journal of surgical oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Hydrocolloid Dressing for the Management of Flap Necrosis Following Cancer Reconstructive Surgery: A Case Report.Cureus · 2026Article
- Article
- Risk stratification of postoperative enteral feeding intolerance using explainable machine learning in oral cancer free flap reconstruction.Frontiers in nutrition · 2026Article
- Perioperative symptom burden as an independent predictor of long-term functional and survival outcomes in oral squamous cell carcinoma patients undergoing free flap reconstruction: a retrospective cohort study.American journal of cancer research · 2026Article
- Pleomorphic Adenoma of a Minor Salivary Gland of the Hard Palate Complicated by Surgical Site Infection: A Case Report.International medical case reports journal · 2026Article
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Authors and funding
6 authors.
Funding
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Abstract
backgroundThis study aimed to ascertain the incidence of flap-related complications in the oral reconstruction area after free flap reconstruction (FFR) in patients with oral cancer (OC).
methodsPubmed, Embase, Cochrane Library, and Web of Science databases were searched for publicly available studies on flap-related complications in the oral reconstruction area after FFR in OC patients until August 2024. Data were extracted, and quality was appraised for eligible studies. The primary outcome indicator was the complication rate in the oral reconstruction area. Meta-analysis was performed using R 4.3.3 software.
resultsA total of 61 studies, involving 4831 patients and 4880 flaps, were included. Meta-analysis demonstrated that the overall incidence of complications in the oral reconstruction area after FFR in OC patients was 24% (95% CI: 0.20-0.28, p < 0.001). Subgroup analysis of complications indicated that the most common complications were wound dehiscence (10%), infections (9%), total/partial flap necrosis (7%), fistula (6%), vascular crises (5%), and bleeding/hematoma (4%) (all P < 0.05).
conclusionThe overall incidence of flap-related complications in the oral reconstruction area is high after FFR in OC patients, with wound dehiscence, infection, and flap necrosis occurring more commonly. Timely detection and proper management of these complications are crucial.
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