Evidence map›Paper›PMID 41152895›Full record

ArticleCritical care (London, England)2025

Respiratory effects of trunk inclination in obese and non-obese patients mechanically ventilated for ARDS.

Martín H Benites, Shailesh Bihari, Romina Battiato, Alejandro Bruhn, Guillermo Bugedo, Eduardo L V Costa, Jean Dellamonica, Claude Guérin, Thomas Langer, John J Marini and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Critical care (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Martín H BenitesCentro de Pacientes Críticos, Clínica las Condes, Santiago, Chile.
Shailesh BihariDepartment of ICU, Flinders Medical Centre, Bedford Park, 5042, South Australia.
Romina BattiatoFacultad de Medicina, Escuela de Medicina, Universidad Nacional de Córdoba, Córdoba, Argentina.
Alejandro BruhnDepartamento de Medicina Intensiva, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
Guillermo BugedoDepartamento de Medicina Intensiva, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
Eduardo L V CostaFaculdade de Medicina, Laboratório de Pneumologia LIM-09, Divisao de Pneumologia, Hospital das Clinicas HCFMUSP, Instituto Do Coracao, Universidade de Sao Paulo, Sao Paulo, Brasil.
Jean DellamonicaUniversité Côte d'Azur, UR2CA, Unité de Recherche Clinique Côte d'Azur, Nice, France.
Claude GuérinUniversité Claude Bernard Lyon I, Faculté de Médecine Lyon-Est, Lyon, France.
Thomas LangerDepartment of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy.
John J MariniDepartment of Pulmonary and Critical Care Medicine, University of Minnesota, Minneapolis, St Paul, MN, USA.
Francesco MarrazoDepartment of Anesthesia and Intensive Care, ASST GOM Niguarda Hospital, Milan, Italy.
Mehdi MezidiMédecine Intensive Réanimation, Hôpital de la Croix-Rousse, Hospices civils de Lyon, Lyon, France.
John SelickmanDepartment of Pulmonary and Critical Care Medicine, University of Minnesota, Minneapolis, St Paul, MN, USA.
Ubbo F WiersemaDepartment of ICU, Flinders Medical Centre, Bedford Park, 5042, South Australia.
Jaime RetamalDepartamento de Medicina Intensiva, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile. jaimeretamal@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAdjusting trunk inclination in patients with acute respiratory distress syndrome directly affects physiological variables such as respiratory mechanics and PaCO

methodsA secondary analysis compared the physiological effects of increasing trunk inclination angles between mechanically ventilated patients with obesity (BMI ≥ 30 kg/m

resultsData from 159 patients collected across seven individual studies were analyzed. The following physiological changes were observed in response to increased trunk inclination: Sixty-five patients with obesity presented a greater decrease in respiratory system compliance (-7.5 [-10; -5] mL/cmH

conclusionsIncreasing the trunk inclination angle during passive ventilation reduces respiratory system, lung, and chest wall compliance. This effect was more pronounced in obese patients. Moreover, only this population exhibited an increase in PaCO

Indexed as

ObesityPostureRespiratory Distress SyndromeAgedBody Mass IndexCarbon DioxideFemaleHumansLungLung ComplianceMaleMiddle AgedRespiratory MechanicsTorsoCarbon DioxideARDSBody positionCompliance of respiratory systemObeseSupine position

Identifiers

PMID41152895
PMCPMC12570651

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.