Evidence map›Paper›PMID 41152877›Full record

ArticleNutrition journal2025

Global trends and age-period-cohort analysis for the disability adjusted life years and mortality of type 2 diabetes mellitus due to diet high in sugar-sweetened beverages.

Ruoting Wang, Changfa Zhang, Ai Zhao, Hertzel C Gerstein, Lehana Thabane, Yingxin Liu, Bo Chen, Gregory Y H Lip, Guowei Li, Harriette G C Van Spall

Abstract read
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Article in Nutrition journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Ruoting WangCenter for Clinical Epidemiology and Methodology (CCEM), The Affiliated Guangdong Second Provincial General Hospital of Jinan University, Guangzhou, 510317, China.
Changfa ZhangCenter for Clinical Epidemiology and Methodology (CCEM), The Affiliated Guangdong Second Provincial General Hospital of Jinan University, Guangzhou, 510317, China.
Ai ZhaoVanke School of Public Health, Tsinghua University, Beijing, 100084, China.
Hertzel C GersteinDepartment of Medicine, McMaster University, Hamilton, ON, Canada.
Lehana ThabaneFather Sean O'Sullivan Research Centre, St. Joseph's Healthcare Hamilton, Hamilton, ON, L8N 4A6, Canada.
Yingxin LiuCenter for Clinical Epidemiology and Methodology (CCEM), The Affiliated Guangdong Second Provincial General Hospital of Jinan University, Guangzhou, 510317, China.
Bo ChenDepartment of Endocrinology, The Affiliated Guangdong Second Provincial, General Hospital of Jinan University, Guangzhou, China.
Gregory Y H LipLiverpool Centre for Cardiovascular Science, University of Liverpool, Liverpool John Moores University and Liverpool Heart & Chest Hospital, Liverpool, UK.
Guowei LiCenter for Clinical Epidemiology and Methodology (CCEM), The Affiliated Guangdong Second Provincial General Hospital of Jinan University, Guangzhou, 510317, China. ligw@gd2h.org.cn.ORCID http://orcid.org/0000-0002-1184-1791
Harriette G C Van SpallDepartment of Medicine, McMaster University, Hamilton, ON, Canada.

Funding

basic research project (Dengfeng Hospital) jointly funded by Guangzhou Science and Technology Bureau and the city school (hospital) 202201020567National Natural Science Foundation of China 82473612Natural Science Foundation of Guangdong Province of China 2025A1515010779Science Foundation of Guangdong Second Provincial General Hospital YY2018-002Young Top Talent Project in Special Support Plan for Training High-level Talents in Guangdong 0720240244
6 · The paper itself

Abstract

backgroundSugar-sweetened beverages (SSBs) are calorie-dense, a possible surrogate for obesogenic food environment, and associated with cardiometabolic diseases. The burden of type 2 diabetes mellitus (T2DM) associated with a diet high in SSBs on a global scale remain unclear. In this study, we examined global trends of disability adjusted life years (DALYs) and mortality of T2DM associated with diet high in SSBs, and explored their associations with age, period, and birth cohort.

methodsUsing data from Global Burden of Disease (GBD) 2021, we estimated the global trends and average annual percentage changes (AAPCs) in age-standardized DALYs and age-standardized mortality of T2DM attributable to diet high in SSBs from 1990 to 2021. Diet high in SSBs was defined as daily consumption of beverages with ≥ 50 kcal per 226.8 g serving on average. Age-period-cohort analyses were conducted to assess the individual contribution of age, period and cohort effects on DALYs and mortality. We used the Nordpred age-period-cohort analysis to forecast global DALYs and mortality for the next 25 years.

resultsFrom 1990 to 2021, there was a continuous annual increase of 2.23% in global age-standardized T2DM DALYs attributable to diet high in SSBs, and a fluctuating increasing trend in mortality with an annual increase of 0.86%. People aged < 60 years experienced a larger increase (AAPC in DALYs and mortality: 2.69% and 1.35%;) in disease burden when compared with adults aged ≥ 60 years (AAPC in DALYs and mortality: 1.86% and 0.74%). The temporal rates were higher in more recent periods (rate ratios for DALYs and mortality: 1.37 and 1.13) and more recently born cohorts (rate ratios for DALYs and mortality: 3.72 and 1.71). The largest DALYs was observed in high socio-demographic index (SDI) countries (56.12 per 100,000 population in 2021). The T2DM burden attributable to diet high in SSBs was projected to increase further, with 22.00% increase in DALYs and 3.02% increase in mortality by 2046.

conclusionThe disease burden of T2DM associated with diet high in SSBs remains a growing health problem globally, especially in younger people. High SDI countries with highest DALYs and elevated mortality require special attention for public health and policy interventions targeting SSBs.

Indexed as

Diabetes Mellitus, Type 2DietDisability-Adjusted Life YearsSugar-Sweetened BeveragesAdultAgedAge FactorsCohort StudiesFemaleGlobal Burden of DiseaseGlobal HealthHumansMaleMiddle AgedAge-period-cohort analysisGlobal burdenSugar-sweetened beveragesType 2 diabetes mellitus

Identifiers

PMID41152877
PMCPMC12570793

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.