Evidence map›Paper›PMID 41152874›Full record

ArticleChild and adolescent psychiatry and mental health2025

Adolescent psychiatric hospitalization: a naturalistic observational study of statistical and clinical outcomes and moderating factors.

Laura Nigro, Alberto Forte, Gregory Mantzouranis, Swen Courosse, Carole Kapp, Maude Schneider, Kerstin Jessica Plessen, Marco Armando, Sébastien Urben

Abstract read
In one paragraph

Article in Child and adolescent psychiatry and mental health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Laura NigroDivision of Child and Adolescent Psychiatry, Department of Psychiatry, Lausanne University Hospital (CHUV), Av. Echallens 9, Lausanne, 1004, Switzerland.
Alberto ForteDivision of Child and Adolescent Psychiatry, Department of Psychiatry, Lausanne University Hospital (CHUV), Av. Echallens 9, Lausanne, 1004, Switzerland.
Gregory MantzouranisThe FAmily and DevelOpment research center (FADO), Faculty of Social and Political Sciences, University of Lausanne, Lausanne, Switzerland.
Swen CourosseDivision of Child and Adolescent Psychiatry, Department of Psychiatry, Lausanne University Hospital (CHUV), Av. Echallens 9, Lausanne, 1004, Switzerland.
Carole KappDivision of Child and Adolescent Psychiatry, Department of Psychiatry, Lausanne University Hospital (CHUV), Av. Echallens 9, Lausanne, 1004, Switzerland.
Maude SchneiderClinical Psychology Unit for Intellectual and Developmental Disabilities, Faculty of Psychology and Educational Sciences, University of Geneva, Geneva, Switzerland.
Kerstin Jessica PlessenDivision of Child and Adolescent Psychiatry, Department of Psychiatry, Lausanne University Hospital (CHUV), Av. Echallens 9, Lausanne, 1004, Switzerland.
Marco Armando *Division of Child and Adolescent Psychiatry, Department of Psychiatry, Lausanne University Hospital (CHUV), Av. Echallens 9, Lausanne, 1004, Switzerland. Marco.Armando@chuv.ch.ORCID https://orcid.org/0000-0001-7074-7212
Sébastien Urben *Division of Child and Adolescent Psychiatry, Department of Psychiatry, Lausanne University Hospital (CHUV), Av. Echallens 9, Lausanne, 1004, Switzerland. Sebastien.urben@chuv.ch.ORCID https://orcid.org/0000-0001-6462-7636

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAdolescents' mental health issues may require psychiatric hospitalization, highlighting the need for effective interventions during hospitalization. This study explored statistical and clinical (through reliable change index; RCI) changes in mental health difficulties across hospitalization and their moderating factors potentially affecting clinical progress and discharge outcomes.

methodsWe examined retrospective socio-demographic and clinical data from 593 adolescents first hospitalized at the Adolescent Psychiatric Hospitalization Unit (UHPA) of the Lausanne University Hospital (CHUV) between 2014 and 2021. Statistical significance (analyzed via t-tests for paired samples) used scores on the Health of the Nation Outcome Scales for Children (HoNOSCA) at admission and discharge, whereas RCI was used to assess clinical significance. Moderating factors were examined through multivariate regression analyses on clinical changes and outcomes at discharge.

resultsStatistically, we observed a significant reduction in mental health issues, as reflected by decreases in the "Total", "Behavioral" and "Symptoms" HoNOSCA scores from admission to discharge. However, clinical improvements (RCI > 1.96) were reached in 20% of patients, while 65% remained stable. Finally, considering moderating factors, while clinical changes during hospitalization remained largely unexplained, moderators such as sex, behavioral and emotional disorders (F9x), antipsychotic intake, voluntary admission, pre-hospitalization occupation, patient-clinician discharge agreement, and length of stay accounted for a significant proportion of clinical outcomes at discharge.

conclusionsWhile hospitalization may contribute to stabilizing acute crises, clinically meaningful improvements were limited for many patients. This highlights the importance of integrative and coordinated approaches tailored to adolescents' heterogeneous profiles.

Indexed as

AdolescentsClinical outcomesHospitalizationReliable change indexRisk factors

Identifiers

PMID41152874
PMCPMC12570707

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.