Evidence map›Paper›PMID 41152766›Full record

ArticleBMC cancer2025

"Who's gonna take care of my babies?" the impact of children on treatment decisions for women with metastatic breast cancer: a qualitative analysis.

Katherine Tomczik, Joshua Niznik, Lorinda A Coombs

Abstract read
In one paragraph

Article in BMC cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Katherine TomczikMedical Student, School of Medicine and Health Sciences, University of North Dakota, 1301 North Columbia Rd, Grand Forks, ND, 58202, USA. katherine.tomczik@und.edu.
Joshua NiznikUniversity of North Carolina Chapel Hill School of Medicine, 5017 Old Clinic CB 7550, Chapel Hill, NC, 27599, USA.
Lorinda A CoombsUniversity of North Carolina Chapel Hill School of Nursing, Carrington Hall, S Columbia S, Chapel Hill, NC, 27599, USA.

Funding

UNC-CH Summer Research Training in Aging for Medical StudentsT35AG038047 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI JAN BUSBY-WHITEHEAD · 2010 to 2026
$1.4M
NIA NIH HHS T35 AG038047UNC-CH Medical Students Training in Aging Research Program NIA 2-T35-AG038047
6 · The paper itself

Abstract

backgroundFew studies have explored the impact that children-and grandchildren-have on treatment decisions in metastatic breast cancer (mBC). This study examined whether or not being a parent or grandparent influences treatment decisions.

methodsA qualitative sub-analysis was conducted with a purposive, diverse sample of 13 women with mBC in the Southeastern United States. Semi-structured interviews explored treatment decision-making, patient values, and patient-clinician communication. Transcribed interviews were analyzed using thematic analysis by three independent coders to identify recurrent themes.

resultsNearly half (n = 6, 46%) of participants were women of color, and 12 had children. Seven themes emerged as key factors in treatment decision-making, with five participants identifying children and grandchildren as critical. Other common factors included side effects (n = 7, 54%) and quality of life (n = 6, 46%). Among participants with children and grandchildren, body image emerged as a subtheme. For those prioritizing quality of life and managing side effects, children provided emotional support and assistance with daily activities.

conclusionsChildren and grandchildren significantly influenced treatment decisions, rivaling quality of life and side effects as critical factors. This influence varied by life stage, with younger mothers prioritizing treatment efficacy and older women valuing quality of life and emotional support. Our results demonstrate that continuous shared decision-making is crucial as treatment preferences evolve and are influenced by familial roles and disease progression. IMPLICATIONS: Future tools should include an assessment that integrates family and children. This approach can better support survivors in aligning treatment with their values and familial priorities.

Indexed as

Breast NeoplasmsDecision MakingIntergenerational RelationsAdultAgedChildFemaleHumansMiddle AgedNeoplasm MetastasisQualitative ResearchQuality of LifeDecision-makingGrandparenthoodMetastatic breast cancerSurvivorshipTreatmentValues

Identifiers

PMID41152766
PMCPMC12570761

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.