Evidence map›Paper›PMID 41152763›Full record

ArticleBMC pediatrics2025

Effect of gestational diabetes on neurodevelopment outcome of the offsprings- Ma'an shan birth cohort study.

Yidan Cao, Tuyan Fan, Rongrong Lu, Jingjing Liu, Tingting Weng, Kun Huang, Hui Gao, Shuangqin Yan, Guopeng Gao, Fengyu Yang and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yidan Cao *Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, No. 81 Meishan Road, Hefei, 230032, Anhui, China.
Tuyan Fan *Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, No. 81 Meishan Road, Hefei, 230032, Anhui, China.
Rongrong Lu *Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, No. 81 Meishan Road, Hefei, 230032, Anhui, China.
Jingjing LiuDepartment of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, No. 81 Meishan Road, Hefei, 230032, Anhui, China.
Tingting WengMa'anshan Maternal and Child Healthcare (MCH) Center, Ma'anshan, 243011, China.
Kun HuangDepartment of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, No. 81 Meishan Road, Hefei, 230032, Anhui, China.
Hui GaoKey Laboratory of Population Health Across Life Cycle, Anhui Medical University, Ministry of Education of the People's Republic of China, No. 81 Meishan Road, Hefei, 230032, Anhui, China.
Shuangqin YanMa'anshan Maternal and Child Healthcare (MCH) Center, Ma'anshan, 243011, China.
Guopeng GaoMa'anshan Maternal and Child Healthcare (MCH) Center, Ma'anshan, 243011, China.
Fengyu YangDepartment of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, No. 81 Meishan Road, Hefei, 230032, Anhui, China.
Fangbiao TaoDepartment of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, No. 81 Meishan Road, Hefei, 230032, Anhui, China.
Beibei ZhuDepartment of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, No. 81 Meishan Road, Hefei, 230032, Anhui, China. a513275541@126.com.ORCID 0000-0002-6724-2034

Funding

the Joint Funds of the National Natural Science Foundation of China Grant No. U22A20361the Key Projects of the Support Programme for Outstanding Young Talents in Higher Education Grant No. gxyqZD2021101the National Natural Science Foundation of China Grant No. 82073564)the Provincial Key Research and Development Project of Anhui Grant No. 202104j07020034
6 · The paper itself

Abstract

backgroundGestational diabetes mellitus (GDM) affects children's neurodevelopmental processes. However, continuous monitoring of this effect across different child age span is lacking. STUDY

design1438 mother-infant pairs were finally include in the analysis. Data of a 75-g oral glucose tolerance test (OGTT) administered to women at 24-28 weeks of pregnancy was collected. Neurodevelopment in childhood was assessed using the Ages and Stages Questionnaires.

resultsAt the age of 6 months, GDM offspring had higher risk of delays in the fine motor domain [aOR = 1.77 (95%CI:1.08 ~ 2.88)]. At the age of 18 months, maternal GDM was associated with delays in the domains of fine motor [aOR = 1.94 (95%CI:1.01 ~ 3.72)] and fasting plasma glucose and 1-hour post-load glucose (1-h PG) were more strongly associated with neurodevelopmental delays compared to 2-hour post-load glucose (2-h PG).

conclusionsThe impaired neurophysiological development risk among offspring born to mothers with GDM increased, particularly evident at 18 months of age and more pronounced in girls.

Indexed as

Child DevelopmentDevelopmental DisabilitiesDiabetes, GestationalNeurodevelopmental DisordersPrenatal Exposure Delayed EffectsAdultBirth CohortBlood GlucoseCohort StudiesFemaleGlucose Tolerance TestHumansInfantMalePregnancyBlood GlucoseChildhood neurodevelopmentGestational diabetes mellitusRepeated measurements

Identifiers

PMID41152763
PMCPMC12570462

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.