ArticleBMC gastroenterology2025
The prevalence of gallstone disease and associated factors among patients who visited the surgical department of Debre Birhan Comprehensive Specialized Hospital, Debre Birhan, Ethiopia: an institution-based cross-sectional study.
Article in BMC gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundThe gallstone disease is gradually becoming a burden of healthcare systems throughout world. The frequency of gallstone disease in Ethiopia has been the subject of few investigations and to the best of our knowledge, limited evidence of published research has examined the risk factors linked with gallstone disease. The main objective of the current study was to assess the prevalence of gallstone disease and associated factors among patients who visited the surgical department of Debre Birhan Comprehensive Specialization Hospital.
methodsThis retrospective institution-based cross-sectional study was conducted at Debre Birhan Comprehensive Specialized Hospital's Surgical Department. A total of 169 patients, aged 18 and above years, were selected between January 2020 and December 2022 using a simple random sampling method. The collected data were analyzed by using SPSS version 25. Descriptive statistics were done, and binary and multiple logistic regression analyses were performed. Risk variables were found using multivariable logistic regression.
resultsThe study included 165 participants, 86 (52.1%) males and 79 (47.9%) females. The mean age of the participants was 41.58 ± 16.185 years. The overall prevalence of gallstone disease was 7.9%, with a greater prevalence observed in women (15.2%) than in men (1.2%). The prevalence of gallstone disease was found to be highest (61.3%) among participants aged between 26 and 45 years, with a Decrease in prevalence after the age of 65 years. Multiple logistic regression analysis revealed that female sex (OR = 6.88), alcohol intake for more than five years (OR = 4.27), and history of gastrointestinal surgery (OR = 6.5) were significantly associated with gallstone disease. Further subgroup multiple logistic regression analysis in females revealed that parity (OR = 8.5) and, after adjusting for alcohol intake, diabetes (OR = 4.6) and hypertension (OR = 1.37) were significantly associated with gallstone disease.
conclusionIn conclusion, the prevalence of gallstone disease was 7.9%, and the disease was fairly common in our study area. Female sex, alcohol intake for more than five years, and a history of gastrointestinal surgery were strongly associated with the occurrence of gallstone disease.
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