ArticleMolecular imaging and biology2025
A Guide to Ex Vivo Biodistribution Studies with Radiotracers in Rodent Models.
Article in Molecular imaging and biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Unlocking the brain: Biodistribution insights into tween 80 nanoliposomes in healthy brains.International journal of pharmaceutics: X · 2026Article
- High Throughput In vivo Imaging; A Pipeline for Automated Analysis of Longitudinal Preclinical Studies.Current protocols · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Preclinical biodistribution studies are required at an early stage of radiopharmaceutical development to determine tracer pharmacokinetics in clinically relevant animal models of human diseases. When combined with quantitative analysis from non-invasive imaging, biodistribution experiments provide essential data on the uptake, retention, binding specificity, metabolism, and clearance of radiotracers in both target and non-target tissues. Most research groups have developed in-house protocols to perform these studies in a reproducible manner. However, there is a general lack of consistency in how different groups carry out biodistribution experiments. In addition to practical differences that occur during tissue collection (for example, washing and blotting dry the tissue, perfusion, sampling site for a given tissue, etc.), other aspects of biodistribution experiments, which often vary include the methods used for calibrating the injected activity, the processes used to calculate mass normalized tissue uptake (i.e. percentage of injected dose per gram [%ID g
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Registered trials
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