Evidence map›Paper›PMID 41152641›Full record

SynthesisInternational journal of clinical oncology2025

Physical activity and risk of thyroid cancer: a systematic review and meta-analysis of prospective cohort studies.

Heram Cho, Yunseo Park, Seung-Kwon Myung

Abstract readSystematic ReviewMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in International journal of clinical oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Heram ChoDepartment of Medicine, Western Sydney University, Campbelltown, NSW, Australia.
Yunseo ParkDepartment of Medicine, Monash University, Clayton, VIC, Australia.
Seung-Kwon MyungDepartment of Public Health & AI, National Cancer Center Graduate School of Cancer Science and Policy, 323 Il San-ro, Ilsandong-gu, Goyang, Gyeonggi-do, 10408, Republic of Korea. msk@ncc.re.kr.ORCID http://orcid.org/0000-0001-8911-1345

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe preventive effect of physical activity on the risk of thyroid cancer remains inconsistent and unclear. We investigated the association between physical activity and the risk of thyroid cancer using a meta-analysis of prospective cohort studies.

methodsA systematic search of PubMed and EMBASE was conducted from inception till December 20, 2024. A pooled relative risk (RR) with its 95% confidence interval (CI) was calculated using an adjusted RR with its 95% CI from each study.

resultsA total of nine prospective cohort studies (N = 2 764 014 adults; incident thyroid cancer cases, 15 166) were included in the final analysis. In the meta-analysis of all the studies, highest physical activity was not significantly associated with the risk of thyroid cancer (RR, 0.91; 95% CI 0.76-1.09; I

conclusionsPhysical activity decreased the risk of thyroid cancer in the studies conducted in Asia, published after 2015, and rated as having high methodological quality. Further high-quality prospective cohort studies are warranted to confirm our findings.

Indexed as

ExerciseThyroid NeoplasmsHumansProspective StudiesRisk FactorsCohort studyMeta-analysisPhysical activitySystematic reviewThyroid cancer

Identifiers

PMID41152641

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.