Evidence map›Paper›PMID 41152603›Full record

ArticleApplied microbiology and biotechnology2025

Versatile sugar and valerate metabolic pathways in Paraburkholderia xenovorans LB400 enable tailored poly(3-hydroxybutyrate-co-3-hydroxyvalerate) production.

Mario I Sepúlveda, Viviana Urtuvia, Natalia Álvarez-Santullano, Pamela Villegas, Jacqueline Vásquez-Navarrete, Valentina Saffirio, Alvaro Díaz-Barrera, Myriam González, Jose Gregório C Gomez, Valentina Méndez and 1 more

Abstract read
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Article in Applied microbiology and biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Mario I SepúlvedaLaboratorio de Microbiología Molecular y Biotecnología Ambiental, Departamento de Química & Centro de Biotecnología Daniel Alkalay Lowitt, Universidad Técnica Federico Santa María, 1680, 2390123, Valparaíso, Chile.
Viviana UrtuviaLaboratorio de Microbiología Molecular y Biotecnología Ambiental, Departamento de Química & Centro de Biotecnología Daniel Alkalay Lowitt, Universidad Técnica Federico Santa María, 1680, 2390123, Valparaíso, Chile.
Natalia Álvarez-SantullanoLaboratorio de Microbiología Molecular y Biotecnología Ambiental, Departamento de Química & Centro de Biotecnología Daniel Alkalay Lowitt, Universidad Técnica Federico Santa María, 1680, 2390123, Valparaíso, Chile.
Pamela VillegasLaboratorio de Microbiología Molecular y Biotecnología Ambiental, Departamento de Química & Centro de Biotecnología Daniel Alkalay Lowitt, Universidad Técnica Federico Santa María, 1680, 2390123, Valparaíso, Chile.
Jacqueline Vásquez-NavarreteLaboratorio de Microbiología Molecular y Biotecnología Ambiental, Departamento de Química & Centro de Biotecnología Daniel Alkalay Lowitt, Universidad Técnica Federico Santa María, 1680, 2390123, Valparaíso, Chile.
Valentina SaffirioLaboratorio de Microbiología Molecular y Biotecnología Ambiental, Departamento de Química & Centro de Biotecnología Daniel Alkalay Lowitt, Universidad Técnica Federico Santa María, 1680, 2390123, Valparaíso, Chile.
Alvaro Díaz-BarreraEscuela de Ingeniería Bioquímica, Pontificia Universidad Católica de Valparaíso, Valparaíso, Av, Chile.
Myriam GonzálezLaboratorio de Microbiología Molecular y Biotecnología Ambiental, Departamento de Química & Centro de Biotecnología Daniel Alkalay Lowitt, Universidad Técnica Federico Santa María, 1680, 2390123, Valparaíso, Chile.
Jose Gregório C GomezDepartment of Microbiology, Institute of Biomedical Sciences, University de São Paulo, São Paulo, Brazil.
Valentina MéndezLaboratorio de Microbiología Molecular y Biotecnología Ambiental, Departamento de Química & Centro de Biotecnología Daniel Alkalay Lowitt, Universidad Técnica Federico Santa María, 1680, 2390123, Valparaíso, Chile.
Michael SeegerLaboratorio de Microbiología Molecular y Biotecnología Ambiental, Departamento de Química & Centro de Biotecnología Daniel Alkalay Lowitt, Universidad Técnica Federico Santa María, 1680, 2390123, Valparaíso, Chile. michael.seeger@usm.cl.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Poly(3-hydroxybutyrate) and poly(3-hydroxybutyrate-co-3-hydroxyvalerate) polymers are accumulated by diverse prokaryotes. Their distinct monomer compositions enable their use as tailored bioplastics. The aims were to characterize the poly(3-hydroxybutyrate) and poly(3-hydroxybutyrate-co-3-hydroxyvalerate) synthesis by Paraburkholderia xenovorans LB400 using different sugars and valerate, and to gain genome-oriented insights into polyhydroxyalkanoate production. d-Glucose, d-mannitol, d-gluconate, and d-xylose were evaluated as sole carbon sources or supplemented with valerate. Polyhydroxyalkanoates synthesized by strain LB400 were characterized through GC-MS, GC-FID, FTIR, and

Indexed as

BurkholderiaceaeMetabolic Networks and PathwaysPolyestersSugarsValeratesPolyhydroxyalkanoatesPolyhydroxybutyratespoly(3-hydroxybutyrate)-co-(3-hydroxyvalerate)PolyestersPolyhydroxyalkanoatesPolyhydroxybutyratesSugarsValeratesGenomeMetabolismParaburkholderia xenovorans; Poly(3-hydroxybutyrate)PHAPoly(3-hydroxybutyrate-co-3-hydroxyvalerate)

Identifiers

PMID41152603
PMCPMC12568896

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.