ArticleJournal of general internal medicine2026
Red Cell Transfusion in General Medicine Patients at Teaching and Non-teaching Hospitals: A Retrospective Cohort Analysis.
Article in Journal of general internal medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Use of platelets and the challenge of adherence to guidelines: Who, when and why?British journal of haematology · 2026Article
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Authors and funding
16 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundRed blood cell transfusion is a well-studied intervention with numerous randomized trials to guide management, yet practice remains highly variable.
objectiveIn this study, we explored hospital and patient factors influencing red cell transfusion in a large multi-center database of hospitalized patients.
designRetrospective analysis
participantsAll adults admitted at hospitals in the GEMINI database-a multi-center inpatient database in Ontario, Canada, between December 2016 and June 2022. MAIN MEASURES: The pre-specified primary analysis compared average treatment effect (ATE) of hemoglobin value on transfusion probability in general internal medicine (GIM) patients by hospital type (teaching or non-teaching) and selected medical diagnoses. KEY
resultsThe primary analysis cohort consisted of 525,510 GIM patients from 24 hospitals. The overall cohort had a 24-h transfusion probability of 79.2% in the < 6.0 g/dL range, 76.2% in the 6.0-6.9 g/dL range, 18.2% in the 7.0-7.9 g/dL range, and 1.1% in the > 8.0 g/dL range. In comparative primary analyses based on medical diagnosis, transfusion probability was higher in the 6.0-6.9 g/dL range for patients presenting to non-teaching hospitals with sickle cell disease (28.7% vs 11.9%, ATE 16.8%, 95% CI 12.6-21.0, p < 0.001), cardiac disease (80.5% vs 75.8%, ATE 4.7%, 95% CI 3.4-5.9, p < 0.001), and gastrointestinal bleeding (87.8% vs 86.1%, ATE 1.8%, 95% CI 0.9-2.6, p < 0.003), and similar for patients with iron deficiency (77% vs 76.5%, ATE 0.5%, 95% CI 0.6-1.6, p = 0.39).
conclusionsIn this longitudinal cohort study, GIM patients with sickle cell and cardiac disease faced substantially different probabilities of red cell transfusion at teaching and non-teaching hospitals.
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