Evidence map›Paper›PMID 41152541›Full record

ArticleScientific reports2025

Evolution of AI in anatomy education study based on comparison of current large language models against historical ChatGPT performance.

Olena Bolgova, Volodymyr Mavrych

Abstract readComparative Study
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Olena BolgovaCollege of Medicine, Alfaisal University, Riyadh, Saudi Arabia.
Volodymyr MavrychCollege of Medicine, Alfaisal University, Riyadh, Saudi Arabia. vmavrych@alfaisal.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The integration of Large Language Models (LLMs) in medical education has gained significant attention, particularly in their ability to handle complex medical knowledge assessments. However, a comprehensive evaluation of their performance in anatomical education remains limited. To evaluate the performance accuracy of current LLMs compared to previous versions in answering anatomical multiple-choice questions and assessing their reliability across different anatomical topics. We analyzed the performance of four LLMs (GPT-4o, Claude, Copilot, and Gemini) on 325 USMLE-style MCQs covering seven anatomical topics. Each model attempted the questions three times. Results were compared with the previous year's GPT-3.5 performance and random guessing. Statistical analysis included chi-square tests for performance differences. Current LLMs achieved an average accuracy of 76.8 ± 12.2%, significantly higher than GPT-3.5 (44.4 ± 8.5%) and random responses (19.4 ± 5.9%). GPT-4o demonstrated the highest accuracy (92.9 ± 2.5%), followed by Claude (76.7 ± 5.7%), Copilot (73.9 ± 11.9%), and Gemini (63.7 ± 6.5%). Performance varied significantly across anatomical topics, with Head & Neck (79.5%) and Abdomen (78.7%) showing the highest accuracy rates, while Upper Limb questions showed the lowest performance (72.9%). Only 29.5% of questions were answered correctly by all LLMs, and 2.5% were never answered correctly. Statistical analysis confirmed significant differences between models and across topics (χ

Indexed as

AnatomyEducational MeasurementEducation, MedicalLanguageGenerative Artificial IntelligenceHumansLarge Language ModelsAnatomyArtificial intelligenceAssessmentChatGPTLarge language modelsMedical education

Identifiers

PMID41152541
PMCPMC12569271

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.