Evidence map›Paper›PMID 41152438›Full record

ArticleHeredity2025

Evidence of long-term purging of mutation burden in killer whale Orcinus orca genomes.

Andrew D Foote, M Thomas P Gilbert, Shyam Gopalakrishnan, Marie Louis, Michael D Martin, Phillip A Morin, Milaja Nykänen, Camilla Hjorth Scharff-Olsen, Laurent Excoffier

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heredity, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Andrew D FooteCMPG, Institute of Ecology and Evolution, University of Bern, Bern, Switzerland. andrew.foote@ibv.uio.no.ORCID http://orcid.org/0000-0001-7384-1634
M Thomas P GilbertNTNU University Museum, Trondheim, Norway.ORCID http://orcid.org/0000-0002-5805-7195
Shyam GopalakrishnanCenter for Evolutionary Hologenomics, The GLOBE Institute, University of Copenhagen, Copenhagen, Denmark.
Marie LouisCenter for Evolutionary Hologenomics, The GLOBE Institute, University of Copenhagen, Copenhagen, Denmark.ORCID http://orcid.org/0000-0002-4611-5503
Michael D MartinNTNU University Museum, Trondheim, Norway.ORCID http://orcid.org/0000-0002-2010-5139
Phillip A MorinMarine Mammal and Turtle Division, Southwest Fisheries Science Center, NMFS, NOAA, La Jolla, CA, USA.ORCID http://orcid.org/0000-0002-3279-1519
Milaja NykänenDepartment of Environmental and Biological Sciences, Saimaa Ringed Seal Research, University of Eastern Finland, Joensuu, Finland.
Camilla Hjorth Scharff-OlsenCenter for Evolutionary Hologenomics, The GLOBE Institute, University of Copenhagen, Copenhagen, Denmark.
Laurent ExcoffierCMPG, Institute of Ecology and Evolution, University of Bern, Bern, Switzerland.ORCID http://orcid.org/0000-0002-7507-6494

Funding

EC | Horizon 2020 Framework Programme (EU Framework Programme for Research and Innovation H2020) 681396European Science Foundation (ESF) ConGenOmicsSchweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (Swiss National Science Foundation) 31003A-143393
6 · The paper itself

Abstract

Genomes of high latitude killer whales (Orcinus orca) harbour signatures of post-glacial founding and expansion. Here, we investigate whether reduced efficacy of selection increased the predicted mutation burden in founder populations with low N

Indexed as

GenomeMutationWhale, KillerAnimalsEvolution, MolecularFounder EffectGenetics, PopulationGenotypeSelection, Genetic

Identifiers

PMID41152438
PMCPMC12678777

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.