ArticleScientific reports2025
Risk factors for postoperative recurrence of deep infiltrating endometriosis during a 6- to 12-year follow-up.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Clinical diagnosis and treatment of bowel endometriosis and the distribution characteristics of lesions.BMC women's health · 2025Article
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Authors and funding
6 authors.
Funding
Abstract
This study aimed to identify risk and protective factors for postoperative recurrence of deep infiltrating endometriosis (DIE). We analyzed 320 patients undergoing laparoscopic excision with ≥ 6 years follow-up at the First Affiliated Hospital of Sun Yat-sen University. Cumulative recurrence rates increased from 7.1% at 6 years to 14.1% by 12 years post-surgery. Multivariate analysis identified left ovarian endometrioma (EMA) as an independent risk factor (HR: 6.413, 95% CI: 2.961-13.889, P < 0.001), while older age (HR: 0.836, 95% CI: 0.788-0.887, P < 0.001), GnRH-a use ≥ 6 months (HR: 0.324, 95% CI: 0.178-0.589, p < 0.001), and postoperative pregnancy (HR: 0.847, 95% CI: 0.179-0.748, p = 0.006) were protective. Gravidity, parity, and unilateral EMA showed univariate associations (P < 0.05), but BMI, dysmenorrhea severity, infertility, and hysterectomy status were nonsignificant. These findings highlight left-side EMA presence was an independent risk factor for the recurrence of deep infiltrating endometriosis after surgery during long-term follow-up. Age, use of GnRH-a for 6 months and postoperative pregnancy were protective factors against recurrence.
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