Evidence map›Paper›PMID 41152225›Full record

ArticleNature communications2025

Three rate-determining protein roles in photosynthetic O

Sarah M Mäusle, Gianluca Parisse, Ricardo Assunção, Cristina De Santis, Philipp S Simon, Daniele Narzi, Leonardo Guidoni, Richard J Debus, Holger Dau

Abstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sarah M Mäusle *Department of Physics, Freie Universität Berlin, Berlin, Germany.ORCID http://orcid.org/0000-0003-1808-8146
Gianluca Parisse *Department of Physical and Chemical Sciences, University of L'Aquila, L'Aquila, Italy.ORCID http://orcid.org/0000-0002-9900-4663
Ricardo AssunçãoDepartment of Physics, Freie Universität Berlin, Berlin, Germany.
Cristina De SantisDepartment of Physical and Chemical Sciences, University of L'Aquila, L'Aquila, Italy.ORCID http://orcid.org/0009-0004-9822-2847
Philipp S SimonDepartment of Physics, Freie Universität Berlin, Berlin, Germany.ORCID http://orcid.org/0000-0002-2859-4475
Daniele NarziDepartment of Physical and Chemical Sciences, University of L'Aquila, L'Aquila, Italy.ORCID http://orcid.org/0000-0003-2731-6286
Leonardo GuidoniDepartment of Physical and Chemical Sciences, University of L'Aquila, L'Aquila, Italy. leonardo.guidoni@univaq.it.
Richard J DebusDepartment of Biochemistry, University of California, Riverside, USA. richard.debus@ucr.edu.ORCID http://orcid.org/0000-0003-1321-8730
Holger DauDepartment of Physics, Freie Universität Berlin, Berlin, Germany. holger.dau@fu-berlin.de.ORCID http://orcid.org/0000-0001-6482-7494

Funding

Deutsche Forschungsgemeinschaft (German Research Foundation) SFB 1078 - Project A4DOE | SC | Basic Energy Sciences (BES) DE-SC0005291
6 · The paper itself

Abstract

Light-driven water splitting by plants, algae and cyanobacteria is pivotal for global bioenergetics and biomass formation. A manganese cluster bound to the photosystem II proteins catalyzes the complex reaction at high rate, but the rate-determining factors are insufficiently understood. Here we trace the oxygen-evolution transition by time-resolved polarography and infrared spectroscopy for cyanobacterial photosystems genetically modified at two strategic sites, complemented by computational chemistry. Our results highlight three rate-determining roles of the protein environment of the metal cluster: acceleration of proton-coupled electron transfer, acceleration of substrate-water insertion after O

Indexed as

Bacterial ProteinsOxygenPhotosynthesisPhotosystem II Protein ComplexCyanobacteriaElectron TransportManganeseThermodynamicsWaterBacterial ProteinsManganeseOxygenPhotosystem II Protein ComplexWater

Identifiers

PMID41152225
PMCPMC12569156

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.